Skip to main content

Table 2 a, b Median ± standard deviation of lymphocyte subpopulations (absolute count in 103/ml) in different subgroups

From: Peripheral blood lymphocytes immunophenotyping predicts disease activity in clinically isolated syndrome patients

a

 

n

T ly

CD4+

CD8+

B ly

NK cells

CD5+

all patients at first relapse

191

1.3 ± 0.4

0.8 ± 0.3

0.4 ± 0.2

0.2 ± 0.1

0.2 ± 0.1

1.3 ± 0.4

all patients at baseline (BL)a

191

1.3 ± 0.4

0.8 ± 0.3

0.5 ± 0.2

0.2 ± 0.1

0.3 ± 0.2

1.3 ± 0.4

all patients at 48 months (48)b

181

1.3 ± 0.5

0.8 ± 0.3

0.4 ± 0.2

0.3 ± 0.2

0.2 ± 0.1

1.3 ± 0.5

patients without relapse at BL

77

1.3 ± 0.3

0.8 ± 0.2

0.4 ± 0.2

0.2 ± 0.1

0.3 ± 0.2

1.3 ± 0.3

patients without relapse at 48b

77

1.3 ± 0.4

0.8 ± 0.2

0.4 ± 0.2

0.3 ± 0.1

0.2 ± 0.1

1.4 ± 0.4

patients with relapse at BL

114

1.3 ± 0.5

0.8 ± 0.3

0.5 ± 0.2

0.2 ± 0.1

0.3 ± 0.1

1.3 ± 0.5

patients with relapse at 48b

104

1.3 ± 0.5

0.8 ± 0.3

0.4 ± 0.2

0.2 ± 0.2

0.2 ± 0.1

1.3 ± 0.6

patients without CPD at BL

154

1.3 ± 0.4

0.8 ± 0.3

0.4 ± 0.2

0.2 ± 0.1

0.2 ± 0.1

1.3 ± 0.4

patients without CPD at 48b

148

1.3 ± 0.5

0.8 ± 0.3

0.4 ± 0.2

0.3 ± 0.2

0.2 ± 0.1

1.4 ± 0.5

patients with CPD at BL

37

1.2 ± 0.4

0.8 ± 0.2

0.3 ± 0.2

0.2 ± 0.1

0.2 ± 0.1

1.2 ± 0.4

patients with CPD at 48b

33

1.1 ± 0.5

0.8 ± 0.3

0.3 ± 0.2

0.3 ± 0.2

0.1 ± 0.1

1.2 ± 0.6

b

 

n

DR+ CD3+

CD45RA+

CD45RA+ CD4+

CD5+ B ly

all patients at first relapse

191

0.1 ± 0.1

1.1 ± 0.4

0.5 ± 0.2

0.04 ± 0.05

all patients at baseline (BL)a

191

0.2 ± 0.1

1.2 ± 0.4

0.5 ± 0.3

0.03 ± 0.05

all patients at 48 months (48)b

181

0.2 ± 0.1

1.1 ± 0.5

0.4 ± 0.2

0.03 ± 0.03

patients without relapse at BL

77

0.2 ± 0.1

1.2 ± 0.3

0.5 ± 0.2

0.03 ± 0.05

patients without relapse at 48b

77

0.2 ± 0.1

1.1 ± 0.4

0.4 ± 0.2

0.03 ± 0.04

patients with relapse at BL

114

0.2 ± 0.1

1.2 ± 0.5

0.5 ± 0.3

0.03 ± 0.04

patients with relapse at 48b

104

0.1 ± 0.1

1.1 ± 0.6

0.4 ± 0.2

0.03 ± 0.03

patients without CDP at BL

154

0.2 ± 0.1

1.2 ± 0.4

0.5 ± 0.3

0.04 ± 0.05

patients without CPD at 48b

148

0.1 ± 0.1

1.1 ± 0.5

0.4 ± 0.2

0.03 ± 0.03

patients with CPD at BL

37

0.1 ± 0.2

1 ± 0.4

0.4 ± 0.2

0.04 ± 0.04

patients with CPD at 48b

33

0.1 ± 0.1

1 ± 0.6

0.3 ± 0.2

0.02 ± 0.03

  1. aThe laboratory test were done before intravenous steroids treatment, interval between this examination and baseline was 2–3 months
  2. bThe results at 48 months of following should be influenced by treatment (natalizumab n = 18, fingolimod n = 3, copaxone n = 6)
  3. T ly – T lymphocytes (CD3+), B ly – B lymphocytes (CD19+), NK cells (CD3-CD16 + 56+)