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Table 4 Multiple linear and logistic regression of SUA level for MMSE score and MCI prevalence

From: Relationship between serum uric acid level and mild cognitive impairment in Chinese community elderly

 

SUA level (continuous)

SUA level (quartiles by gender)

MMSE score

β(95% CI)

P

Q1

Q2 β(95% CI)

Q3 β(95% CI)

Q4 β(95% CI)

P trend

 Participants with hyperuricemia

  Male

−0.03(−0.56–0.39)

0.721

1.00(Ref)

0.97(0.66–1.43)

0.92(0.58–1.26)

0.99(0.87–1.13)

0.544

  Female

−0.01(−0.43–0.37)

0.882

1.00(Ref)

1.07(0.80–1.27)

1.05(0.78–1.31)

1.00(0.92–1.18)

0.922

 Participants without hyperuricemia

 

  Male

0.14(0.04–0.42)

0.048

1.00(Ref)

1.01(0.69–1.48)

1.50(0.85–2.64)

1.65(1.12–2.43)

0.027

  Female

0.28(0.02–0.53)

0.037

1.00(Ref)

1.53(1.00–2.33)

1.84(1.27–2.90)

1.92(1.02–3.35)

0.017

Prevalence of MCI

OR (95% CI)

P

Q1

Q2 OR (95% CI)

Q3 OR (95% CI)

Q4 OR (95% CI)

P trend

 Participants with hyperuricemia

  Male

1.06(0.47–1.64)

0.126

1.00(Ref)

0.48(0.10–2.33)

0.54(0.12–2.40)

0.10(0.01–0.97)

0.256

  Female

1.02(0.67–1.56)

0.915

1.00(Ref)

0.59(0.18–1.90)

0.32(0.08–1.23)

1.08(0.36–3.20)

0.246

Participants without hyperuricemia

  Male

0.82(0.68–0.99)

0.047

1.00(Ref)

0.95(0.50–1.78)

0.91(0.49–1.70)

0.72(0.38–1.36)

0.025

  Female

0.80(0.65–0.97)

0.034

1.00(Ref)

0.87(0.45–1.70)

0.72(0.44–1.77)

0.64(0.39–1.06)

0.008

  1. Adjusted for age, education, marital status, BMI, current smoking, current drinking, physical activity ≥ 0.5 h/day, family history of dementia, hypertension, cerebral vascular disease and diabetes