Table 4 SIR and 95% confidence intervals calculations for MS patients exposed or not to IS drugs. Comparison were made with respect to the Sicilian general population in the correspondent age classes
From: Association between multiple sclerosis, cancer risk, and immunosuppressant treatment: a cohort study
Age | Exposed to IS | Not exposed to IS | ||||
|---|---|---|---|---|---|---|
No. | Expected | Observed | No. | Expected | Observed | |
15–19 | 1 | 0,00035 | 0 | 2 | 0,0007 | 0 |
20–24 | 2 | 0,00100 | 0 | 9 | 0,0050 | 0 |
25–29 | 17 | 0,01200 | 0 | 28 | 0,0210 | 0 |
30–34 | 35 | 0,03600 | 0 | 41 | 0,0420 | 0 |
35–39 | 71 | 0,10,000 | 1 | 61 | 0,0900 | 0 |
40–44 | 66 | 0,16,000 | 2 | 78 | 0,1900 | 0 |
45–49 | 87 | 0,30,000 | 1 | 78 | 0,2700 | 1 |
50–54 | 90 | 0,48,000 | 3 | 59 | 0,3160 | 0 |
55–59 | 62 | 0,47,000 | 1 | 56 | 0,4280 | 0 |
60–64 | 48 | 0,51,000 | 2 | 52 | 0,5500 | 0 |
65–69 | 35 | 0,52,000 | 0 | 34 | 0,5100 | 1 |
70–74 | 13 | 0,24,000 | 3 | 17 | 0,3100 | 0 |
75–79 | 4 | 0,08600 | 0 | 7 | 0,1500 | 0 |
80–84 | 0 | 0,00000 | 0 | 6 | 0,1400 | 1 |
85+ | 0 | 0,00000 | 0 | 3 | 0,0650 | 0 |
Total | 531 | 2,91,535 | 13 | 531 | 3,0877 | 3 |
SIR | Tot | 4,12 | 0,97 | |||