Fig. 4

EAE animals walk slower (body and swing speed) and with short footsteps (stride length). No differences between EAE and EAE-Ex groups at any time point for any of the parameters can be observed. a Front paws stride length. EAE-Ex (dashed line): Basal and 5 dpi vs 22 and 28 dpi (p < 0.05). b Hind paws stride length. EAE-Ex (dashed line): Basal and 5 dpi vs 19, 22 and 28 dpi (p < 0.05). c Front paws body speed. EAE-Ex (dashed line): 5 dpi vs 22 and 28 dpi (p < 0.05). d Hind paws body speed. EAE-Ex (dashed line): 5 dpi vs 22 and 28 dpi (p < 0.05). e Front paws swing speed. No differences detected. f Hind paws swing speed. EAE (continuous line): Basal vs 28 dpi (p < 0.05). EAE-Ex (dashed line): 5 dpi vs 12–42 dpi (p < 0.05) and Basal vs 22 and 28 dpi (p < 0.05)