Fig. 6

EAE animals present reduced intensity of paw prints at chronic disease. ⁺ p < 0.05 and ⁺⁺ p < 0.01 between EAE and EAE-Ex groups. a Front paws max contact max intensity. EAE (continuous line): Basal vs 36 dpi (p < 0.05) and Basal to 22 dpi vs 42 dpi (p < 0.05). EAE-Ex (dashed line): Basal vs 36 dpi (p < 0.05) and Basal, 5, 19 and 22 dpi vs 42 dpi (p < 0.05). b Hind paws max contact max intensity. EAE (continuous line): Basal vs 25, 28 and 42 dpi (p < 0.05) and 5 dpi vs 42 dpi. EAE-Ex (dashed line): Basal vs 28 and 42 dpi (p < 0.05) and 5 dpi vs 28 dpi. c Front paws mean intensity of the 15 most intense pixels. EAE (continuous line): Basal vs 42dpi (p < 0.05). EAE-Ex (dashed line): Basal vs 12, 36 and 42 dpi (p < 0.05). d Hind paws mean intensity of the 15 most intense pixels. EAE (continuous line): Basal and 5 dpi vs 25, 28 and 42 dpi (p < 0.05). EAE-Ex (dashed line): Basal vs 12–42 dpi (p < 0.05) and 5 dpi vs 28 dpi (p < 0.05). + Represents p < 0.05 between EAE and EAE-Ex at Basal time point. e Front paws max intensity at. EAE (continuous line): Basal, 5 and 12 dpi vs 22–42 dpi (p < 0.05) and 19 dpi vs 28 dpi (p < 0.05). EAE-Ex (dashed line): Basal vs 22 and 31 dpi (p < 0.05) and 5 dpi vs 31 dpi (p < 0.01). ++ Represents p < 0.01 between EAE and EAE-Ex at Basal time point. f Hind paws max intensity at. EAE (continuous line): Basal and 5 dpi vs 19–42 dpi (p < 0.01) and 12 dpi vs Basal, 5, 25, 28, 36 and 42 dpi (p < 0.05). EAE-Ex (dashed line): Basal and 5 dpi vs 12–42 dpi (p < 0.05) and 12 dpi vs 22–42 dpi (p < 0.05). g Front paws max contact at. + Represents p < 0.05 between EAE and EAE-Ex at Basal time point. h Hind paws max contact at. EAE (continuous line): 5 dpi vs 19, 28 and 36 dpi