Table 1 Summary of the demographic, clinical and biomarker data of the AIS patients

 Age (years)

71 (±14)

 Gender (female/male)

23/27

 Time to CSF sampling, at admission (h)

8.7 (± 6.2)

 Time to plasma sampling, at admission (h)

5.2 (± 5.8)

 Ischemic stroke/ transient ischemic attack

40/10

 NIHSS at admission

6.8 (±7.8)

 mRS at 3 months

2.4 (±1.9)

 mRS at 12 months

2.1 (±2.3)^a

 Infarct volume (mL)

26.0 (±50.1)^b

 Shortest distance between infarct and ventricles (mm)

5.5 (±8.6)^b

 - Lacunar stroke syndrome

8 (±16.0)

 - Partial anterior circulation syndrome

20 (±40.0)

 - Total anterior circulation stroke

8 (±16.0)

 - Posterior circulation syndrome

12 (±24.0)

TOAST classification:

 - Lacunar

8 (±16.0)

 - Atherothrombotic

6 (±12.0)

 - Cardioemboligenic

17 (±34.0)

 - Specific

4 (±8.0)

 - Undetermined

13 (±26.0)

 - Mimic

2 (±4.0)

 CSF neurogranin (pg/mL)

380 (279–482)

 CSF tau (pg/mL)

434 (322–535)