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Table 4 Value of tau as plasma AIS biomarker reflecting stroke severity and long-term outcome

From: Neurogranin and tau in cerebrospinal fluid and plasma of patients with acute ischemic stroke

  

AUC value

P-value

NIHSS

At admission

0.581

0.355

24 h

0.701

0.022

72 h

0.751

0.004

7d

0.730

0.009

1 m

0.672

0.113

3 m

0.518

0.890

mRS 12 m

At admission

0.638

0.198

24 h

0.645

0.180

72 h

0.750

0.019

7d

0.804

0.005

1 m

0.850

0.027

3 m

0.783

0.348

  1. Severity (NIHSS) or outcome at 12 months (mRS 12 m) were first dichotomized: patients with NIHSS scores ≤7 were pooled versus NIHSS >7, or with mRS scores 0–3 versus scores 4–6. ROC analysis was performed at all time points on both groups for tau, quantified by ELISA. Statistically significant AUC-values are in bold font and underlined