Skip to main content

Table 4 Deep gray matter data: between group and between field strength comparisons

From: Automated segmentation of cerebral deep gray matter from MRI scans: effect of field strength on sensitivity and reliability

   MS group (n = 14) NC group (n = 15) pa, b MS vs NC
  DGM structure 1.5T 3T p (MS) 1.5T vs. 3T 1.5T 3T P (NC) 1.5T vs 3T 1.5T 3T
Volumes (ml) Thalamus 14.4 (1.4)
11.7–16.3
14.7 (1.5)
12.6–16.7
0.003 15.2 (1.0)
12.9–16.3
16.0 (1.0)
13.6–17.1
<0.0001 0.05 0.02
Caudate 6.2 (0.9)
4.9–7.8
6.5 (0.9)
5.0–8.2
0.0001 6.9 (0.8)
5.2–8.6
7.3 (0.9)
5.6–9.4
<0.0001 0.09 0.10
Putamen 8.7 (0.7)
7.4–9.7
9.0 (0.7)
7.6–10.1
<0.0001 9.6 (0.8)
8.6–11.7
10.1 (0.9)
9.1–12.6
<0.0001 0.03 0.02
Globus pallidus 2.9 (0.3)
2.4–3.4
3.1 (0.4)
2.6–3.9
0.0004 3.3 (0.3)
2.9–3.7
3.6 (0.3)
3.2–4.0
<0.0001 0.0006 0.0004
Total DGM 32.2 (2.8)
26.4–37.1
33.4 (3.0)
28.1–38.6
<0.0001 35.0 (2.6)
30.9–40.2
37.0 (2.6)
32.8–42.8
<0.0001 0.02 0.01
Fractions Thalamus 0.011 (0.0011)
0.0087–0.013
0.012 (0.00097)
0.0096–0.013
0.12 0.0116 (0.00058)
0.010–0.013
0.012 (0.00063)
0.011–0.013
0.0004 0.31 0.23
Caudate 0.0049 (0.00057)
0.0037–0.0056
0.0051 (0.00058)
0.0040–0.0059
0.007 0.0053 (0.00046)
0.0040–0.0060
0.0055 (0.00053)
0.0043–0.0066
0.0004 0.20 0.30
Putamen 0.0068 (0.00055)
0.0055–0.0078
0.0071 (0.00057)
0.0057–0.0080
0.0001 0.0074 (0.00051)
0.0065–0.0081
0.0077 (0.00053)
0.0068–0.0088
<0.0001 0.20 0.20
Globus pallidus 0.0023 (0.00021)
0.0018–0.0026
0.0024 (0.00024)
0.0020–0.0028
0.0002 0.0025 (0.00017)
0.0023–0.0028
0.0028 (0.00013)
0.0025–0.0030
<0.0001 0.009 0.003
Total DGM 0.0252 (0.0020)
0.0197–0.0282
0.0261 (0.0019)
0.0213–0.0280
0.002 0.0268 (0.0013)
0.0236–0.0290
0.0282 (0.0013)
0.0256–0.0299
<0.0001 0.11 0.07
  1. Key: Data are mean (standard deviation) on first line; range on second line; Percent differences between 1.5T and 3T are shown in Table 5; DGM = cerebral subcortical deep gray matter; MS multiple sclerosis, NC normal controls; aage adjusted; bthe differentiation (sensitivity) between MS and NC was similar for 1.5 versus 3T (all p > 0.05)