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Table 2 Persistence, adherence, and compliance stratified by age, gender, baseline EDSS score, and participation in BETAPLUS programme

From: Adherence, satisfaction and functional health status among patients with multiple sclerosis using the BETACONNECT® autoinjector: a prospective observational cohort study

  Week 4 Week 12 Week 24
Number of persistent patients (%)
Total (FAS, N = 143) 90.2 86.0 74.8
Age
  < 40 (N = 69) 89.9 84.1 69.6
  ≥ 40 (N = 74) 90.5 87.8 79.7
Gender
 Female (N = 99) 90.9 83.8 73.7
 Male (N = 44) 88.6 90.9 77.3
EDSS baseline score
  < 3 (N = 90) 92.2 90 78.9
  ≥ 3 (N = 34) 91.2 85.3 67.7
Previous treatment with IFN beta-1b
 Yes (N = 106) 89.6 84.0 70.8
 No (N = 37) 91.9 91.9 86.5
BETAPLUS participation
 Yes (N = 87) 87.4 81.6 70.1
 No (N = 56) 94.6 92.9 82.1
Number of adherent patients (%) among all patients with at least one data readout from Betaconnect
Total (N = 107) 72.0 67.3 58.0
Age
  < 40 (N = 46) 71.7 65.2 56.5
  ≥ 40 (N = 61) 72.1 68. 59.0
Gender
 Female (N = 75) 74.7 66.7 57.3
 Male (N = 32) 65.6 68.8 59.4
EDSS baseline score
  < 3 (N = 67) 76.1 71.6 58.2
  ≥ 3 (N = 27) 63.0 55.6 55.6
Previous treatment with IFN beta-1b
 Yes (N = 75) 68.0 62.7 49.3
 No (N = 32) 81.3 78.1 78.1
BETAPLUS participation
 Yes (N = 69) 76.8 69.6 59.4
 No (N = 38) 63.2 63.2 55.3
Number of adherent patients (%) among all patients with data from corresponding visit
  N % N % N %
Total 95 81.1 83 86.8 77 80.5
Age
  < 40 years 40 82.5 34 88.2 30 86.7
  ≥ 40 55 80 49 85.7 47 76.6
Gender
 Female 66 84.9 57 87.7 53 81.1
 Male 29 72.4 26 84.6 24 79.2
EDSS baseline score
  < 3 59 86.4 54 88.9 47 83.0
  ≥ 3 24 70.8 18 83.33 19 79.0
Previous treatment with IFN beta-1b
 Yes 66 77.3 56 83.9 50 74.0
 No 29 89.7 27 92.6 27 92.6
BETAPLUS participation
 Yes 61 86.9 53 90.6 49 83.7
 No 34 70.6 30 80.0 28 75.0
Mean compliance (%) among all patients with data from corresponding visit
Total 95 86.3 83 91.9 77 92.9
Age
  < 40 years 40 87.1 34 93.2 30 94.8
  ≥ 40 55 85.2 49 91.0 47 91.6
Gender
 Female 66 88.8 57 91.5 53 93.47
 Male 29 80.7 26 92.8 24 91.6
EDSS baseline score
  < 3 59 89.72 54 93.5 47 94.9
  ≥ 3 24 79.4 18 89.4 19 90.4
Previous treatment with IFN beta-1b
 Yes 66 84.5 56 91.1 50 90.2
 No 29 90.4 27 93.4 27 97.8
BETAPLUS participation
 Yes 61 91.2 53 93.4 49 93.9
 No 34 77.6 30 89.1 28 91.0
  1. FAS full analysis set, EDSS expanded disability status scale, IFN interferon