| DC (n = 535) | VC (n = 248) | p-Value |
---|---|---|---|
Clinical data, median (IQR) | |||
 Age (y) | 71 (60–78) | 69 (61–77) | 0.924 |
 DBP (mm Hg) | 90 (80–100) | 100 (80–100) | 0.025 |
 Height (m) | 1.65 (1.6–1.72) | 1.65 (1.58–1.71) | 0.063 |
 Male sex, n (%) | 289 (54) | 125 (50.4) | 0.346 |
 NIHSS | 8 (4–16) | 8 (4–16) | 0.574 |
 Pulse rate (bpm) | 78 (74–83) | 78 (74–85) | 0.155 |
 SBP (mm Hg) | 160 (140–180) | 160 (140–180) | 0.19 |
 Time from onset (h) | 5.5 (2–11) | 6 (2.5–11) | 0.265 |
 Temperature (°C) | 36.6 (36.4–36.6) | 36.6 (36.5–36.6) | 0.194 |
 Weight (kg) | 78 (68–88) | 76.7 (68–85) | 0.476 |
Stroke cause, n (%) | |||
 Large-artery atherosclerosis | 212 (39.6) | 109 (44) | 0.252 |
 Cardioembolism | 225 (42.1) | 101 (40.7) | 0.725 |
 Small-vessel occlusion | 79 (14.8) | 33 (13.3) | 0.587 |
 Other determined etiology | 7 (1.3) | 1 (0.4) | 0.241 |
 Undetermined etiology | 12 (2.2) | 4 (1.6) | 0.562 |
Risk factors, n (%) | |||
 Acute myocardial infarction | 25 (4.7) | 8 (3.2) | 0.348 |
 AF history | 210 (39.3) | 94 (37.9) | 0.719 |
 Alcohol abuse | 62 (11.6) | 29 (11.7) | 0.966 |
 Atherosclerosis | 528 (98.7) | 248 (100) | 0.07 |
 Bleeding history | 41 (7.7) | 27 (10.9) | 0.136 |
 Chronic heart failure | 62 (11.6) | 28 (11.3) | 0.903 |
 Chronic liver failure | 5 (0.9) | 7 (2.8) | 0.045 |
 Chronic renal failure | 20 (3.7) | 11 (4.4) | 0.642 |
 Coronary artery disease | 191 (35.7) | 89 (35.9) | 0.96 |
 Diabetes mellitus | 142 (26.5) | 69 (27.8) | 0.707 |
 Dyslipidemia | 216 (40.4) | 103 (41.5) | 0.759 |
 Hypertension | 497 (92.9) | 230 (92.7) | 0.937 |
 Malignancy | 10 (1.9) | 4 (1.6) | 0.801 |
 Seizures at onset | 10 (1.9) | 3 (1.2) | 0.502 |
 Previous TIA/stroke | 221 (41.3) | 116 (46.8) | 0.151 |
Brain CT, n (%) | |||
 ASPECTS, median (IQR) | 8 (6–9) | 8 (6–9) | 0.708 |
 HMCA sign | 141 (26.4) | 66 (26.6) | 0.939 |
 Leukoaraiosis | 347 (64.9) | 168 (67.7) | 0.429 |
 Left hemispheric stroke | 286 (53.5) | 122 (49.2) | 0.266 |
 Right hemispheric stroke | 234 (43.7) | 122 (49.2) | 0.154 |
 Bihemispheric stroke | 15 (2.8) | 4 (1.6) | 0.314 |
Blood tests, median (IQR) | |||
 Albumin (g/L), n = 513/233 | 41.1 (38.6–43.1) | 40.7 (38.8–42.9) | 0.612 |
 ALT (IU/L), n = 531/248 | 20 (14–28) | 19 (13.2–29.8) | 0.48 |
 AST (IU/L), n = 495/227 | 24 (19–31) | 23 (19–32) | 0.939 |
 APTT (s) | 32 (28.8–35.3) | 31.9 (28.7–34.5) | 0.299 |
 Bilirubin, total (μmol/L), n = 497/231 | 11.5 (8.3–17) | 11.5 (8–16.1) | 0.699 |
 Cholesterol, total (mmol/L), n = 467/209 | 5.1 (4.3–5.9) | 5.2 (4.3–6.1) | 0.286 |
 Creatinine (μmol/L) | 90.6 (79.3–106) | 90 (77.4–108) | 0.851 |
 Fibrinogen (g/L), n = 502/240 | 3.2 (2.6–4) | 3.2 (2.6–4.2) | 0.985 |
 Glucose (mmol/L) | 6.8 (5.9–8.3) | 6.8 (5.9–8.1) | 0.998 |
 Hematocrit, n = 534/247 | 0.43 (0.38–0.46) | 0.42 (0.37–0.45) | 0.08 |
 Hemoglobin (g/L), n = 535/247 | 141 (128–153) | 139 (124–150) | 0.12 |
 INR | 1.04 (0.96–1.15) | 1.05 (0.98–1.15) | 0.361 |
 Platelet count (×109 cells/L) | 245 (199–306) | 249.5 (201–301) | 0.865 |
 Protein, total (g/L), n = 523/242 | 67.9 (64.4–71.7) | 68.4 (64.7–72.7) | 0.159 |
 Potassium (mmol/L), n = 530/243 | 4 (3.7–4.3) | 4 (3.7–4.3) | 0.223 |
 PT (s), n = 531/247 | 12 (10.9–14.8) | 12 (11.2–15.3) | 0.408 |
 RBC (×1012 cells/L) | 4.63 (4.28–4.97) | 4.55 (4.14–4.93) | 0.032 |
 Sodium (mmol/L), n = 530/242 | 139.5 (138–141.3) | 139.1 (137–141) | 0.164 |
 Urea (mmol/L), n = 533/248 | 6 (4.7–7.7) | 5.7 (4.6–7.6) | 0.403 |
 WBC (×109 cells/L) | 7.9 (6.5–9.7) | 7.6 (6.3–9.5) | 0.285 |
ECG, n (%) | |||
 AF rhythm | 164 (30.7) | 77 (31) | 0.911 |
 HR (bpm), median (IQR) | 79 (67–91) | 80 (68–96) | 0.157 |
 Normal ECG | 26 (4.9) | 10 (4) | 0.607 |
 Other ECG changes | 259 (48.4) | 121 (48.8) | 0.921 |
LVEF (%), n = 486/217, median (IQR) | 57 (50–60) | 57 (50–61) | 0.993 |
Chest X-ray, n (%) | |||
 Aortic atherosclerosis | 462 (86.4) | 217 (87.5) | 0.661 |
 Cardiomegaly | 401 (75) | 207 (83.5) | 0.008 |
 Normal chest X-ray | 28 (5.2) | 13 (5.2) | 0.996 |
 Pleural effusion | 62 (11.6) | 20 (8.1) | 0.134 |
 Pneumonia | 48 (9) | 23 (9.3) | 0.891 |
 Pulmonary congestion | 215 (40.2) | 109 (44) | 0.32 |
Antithrombotic medication, n (%) | |||
 Anticoagulant | 28 (5.2) | 14 (5.6) | 0.812 |
 Antiplatelet | 390 (73) | 201 (81) | 0.014 |
 Anticoagulant + antiplatelet | 66 (12.3) | 17 (6.9) | 0.02 |
 IV rtPA | 51 (9.5) | 16 (6.5) | 0.152 |
Outcome, n (%) | |||
 Any HT | 126 (23.6) | 60 (24.2) | 0.844 |
 SHT | 69 (12.9) | 29 (11.7) | 0.636 |
 HI-1 | 22 (4.1) | 4 (1.6) | 0.069 |
 HI-2 | 82 (15.3) | 38 (15.3) | 0.999 |
 PH-1 | 9 (1.7) | 4 (1.6) | 0.944 |
 PH-2 | 13 (2.4) | 14 (5.6) | 0.022 |
 Death | 34 (6.4) | 19 (7.7) | 0.499 |
 Malignant cerebral edema | 32 (6) | 14 (5.6) | 0.852 |
 Dependency | 325 (60.7) | 147 (59.3) | 0.695 |