Table 1 Demographical characteristics and neuropsychiatric tests in 132 Alzheimer’s disease
From: Effects of Homocysteine on white matter diffusion parameters in Alzheimer’s disease
Mean | ± | SD | Hcy correlation※ | P value | |
|---|---|---|---|---|---|
Age | 73.5 | ± | 7.5 | 0.12 | 0.19 |
Education (year) | 7.2 | ± | 4.8 | 0.07 | 0.44 |
Apolipoprotein E4 carrier (positive case, %) | 58 (43.9%) | – | |||
Sex (male/female) | 63/69 | – | |||
Mini-Mental State Examination | 20.1 | ± | 6.5 | 0.00294 | 0.97 |
CASI total scores | 67.4 | ± | 21.1 | 0.01 | 0.89 |
CASI executive function test scores | 25.1 | ± | 8.3 | −0.01 | 0.87 |
CASI Subdomains | ± | ||||
Short Term Memory | 5.4 | ± | 3.7 | 0.00087 | 0.99 |
Orientation | 12.7 | ± | 5.3 | −0.02 | 0.86 |
Long Term Memory | 8.3 | ± | 2.5 | 0.08 | 0.36 |
Language | 8.1 | ± | 2.3 | 0.01 | 0.93 |
Drawing | 7.9 | ± | 2.8 | 0.10 | 0.26 |
Attention | 6.3 | ± | 1.4 | −0.04 | 0.65 |
Verbal fluency | 5.2 | ± | 2.8 | −0.06 | 0.51 |
Abstract thinking | 8.1 | ± | 2.9 | 0.02 | 0.85 |
Mental manipulation | 5.5 | ± | 3.3 | 0.01 | 0.88 |
Cerebrovascular Risk Biomarkers | |||||
High sensitive C reactive protein (mg/L) | 2.7 | ± | 4.9 | −0.13 | 0.14 |
Homocysteine [Hcy] (umol/L) | 12.7 | ± | 4.4 | – | – |
Hemoglobin-A1C (%) | 6.2 | ± | 1.1 | 0.00069 | 0.99 |
Creatinine (mg%) | 0.9 | ± | 0.4 | 0.54 | 3.7 × 10−11 |
Glomerular filtration rate (mL/min) | 74.7 | ± | 20.5 | −0.47 | 1.4 × 10−8 |
high-density lipoprotein (mg/dl) | 58.0 | ± | 17.0 | −0.22 | 0.01 |
low-density lipoprotein (mg/dl) | 104.8 | ± | 36.6 | 0.01 | 0.95 |
Hemoglobin (mg/dl) | 13.4 | ± | 1.6 | 0.01 | 0.93 |
Total Cholesterol (mg/dl) | 187.5 | ± | 39.9 | −0.07 | 0.43 |
Triglyceride (mg/dl) | 119.3 | ± | 60.6 | 0.09 | 0.31 |
Vitamin B12 (pg/dl) | 608.4 | ± | 341.1 | −0.36 | 2.7 × 10−5 |
Folate (ng/dl) | 12.2 | ± | 5.6 | −0.40 | 1.6 × 10−6 |