Fig. 4
From: Neuroprotective effect of neuroserpin in non-tPA-induced intracerebral hemorrhage mouse models
Morphological assays for occludin-expressing cells by IHC + Hoechst. In the sham48h group, occludin-expressing cells (bright green spots) distributed regularly, surrounding the capillaries (the distribution pattern is shown with a solid red ring), whereas in the ICH group, we could not find this pattern; the distribution of occludin-expressing cells became irregular. No occludin-expressing cell was found surrounding the capillaries (dotted red ring). After NSP administration (ICH48h + NSP), the occludin-expressing cells redistributed surrounding the capillaries, and the distribution pattern was observed again (solid red ring)