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Table 4 Univariate and Multivariable Analysis for Biochemical Predictors of PSD in Patients With ACI

From: Predictors of early-onset post-ischemic stroke depression: a cross-sectional study

 

Univariate

Multivariate

OR (95% CI)

P value

OR (95% CI)

P value

TT3, μg/L

0.00(0.000,0.04)

< 0.001#

  

TT4, μg/L

0.99(0.95,1.03)

0.582

  

TSH, uIU/mL

1.15(0.66,2.03)

0.625

  

LDL, mmol/L

0.89(0.56,1.41)

0.618

  

HDL, mmol/L

0.66(0.17,2.56)

0.438

  

FBG, mmol/L

1.11(0.90,1.36)

0.337

  

2hPBG, mmol/L

1.03(0.94,1.13)

0.543

  

HbA1c, %

0.97(0.74,1.26)

0.790

  

NE, ng/L

0.99(0.99,0.99)

< 0.001#

  

DA, ng/L

0.85(0.79,0.90)

< 0.001#

0.64(0.45,0.91)

0.014*

5-HT, ng/L

0.99(0.99,1.00)

< 0.001#

0.99(0.98,1.00)

0.046*

IL-6, ng/L

3.23(1.90,5.48)

< 0.001#

  

TNF-α, ng/L

1.03(1.02,1.04)

< 0.001#

1.05(1.00,1.09)

0.044*

NGF, ng/L

0.55(0.41,0.76)

< 0.000#

0.06(0.01,0.67)

0.022*

CGRP, pg/ml

1.03(0.99,1.07)

0.146

  
  1. CI confidence interval, CGRP calcitonin gene-related peptide, DA dopamine, FBG fasting blood glucose, 5-HT 5-hydroxytryptamine, HbA1c glycosylated hemoglobin, type A1c, HDL high-density lipoprotein, IL-6 interleukin 6, LDL low-density lipoprotein, NE norepinephrine, NGF nerve growth factor, OR odds ratio, 2hPBG 2-h postprandial blood glucose, PSD post-stroke depression, SD standard deviation, TNF-α tumor necrosis factor-α, TSH thyroid-stimulating hormone, TT3 total triiodothyronine, TT4 total thyroxine
  2. * P < 0.05; # P < 0.001
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BMC Neurology

ISSN: 1471-2377

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