Table 4 genotype and allele frequencies of patients with IAs vs. controls
From: CDKN2BAS gene polymorphisms and the risk of intracranial aneurysm in the Chinese population
Aneurysms | Controls | X2 value | P value | OR(95%CI) | ||
|---|---|---|---|---|---|---|
rs1333040 | CC | 19(9.5) | 18(9) | 8.545 | 0.014 | |
CT | 65(32.5) | 92(46) | ||||
TT | 116(58) | 90(45) | ||||
CC + CT | 84(42) | 111(55.5) | 7.295 | 0.007 | 1.722(1.159—2.558) | |
C allele | 103/297(25.75) | 128/272(32) | 3.804 | 0.051 | 0.737(0.542—1.002) | |
rs3217986 | AA | 166(83) | 157(78.5) | 1.597 | 0.445 | |
AC | 32(16) | 39(19.5) | ||||
CC | 2(1) | 4(2) | ||||
AC + CC | 34(17) | 43(21.5) | 1.303 | 0.254 | 0.748(0.454—1.233) | |
rs10757272 | CC | 21(10.5) | 22(11) | 0.497 | 0.780 | |
CT | 97(48.5) | 90(45) | ||||
TT | 82(41) | 88(44) | ||||
CC + CT | 112(56) | 111(55.5) | 0.368 | 0.544 | 1.131(0.760—1.681) | |
rs6475606 | CC | 19(9.5) | 17(8.5) | 10.961 | 0.004 | |
CT | 63(31.5) | 95(47.5) | ||||
TT | 118(59) | 88(44) | ||||
CC + CT | 82(41) | 112(56) | 9.008 | 0.003 | 1.831(1.232—2.723) | |
C allele | 101/299(25.25) | 129/271(32.25) | 4.784 | 0.029 | 0.710(0.522—0.966) | |
rs1063192 | CC | 6(3) | 5(2.5) | 0.783 | 0.676 | |
CT | 56(28) | 49(24.5) | ||||
TT | 138(69) | 146(73) | ||||
CC + CT | 62(31) | 54(27) | 0.777 | 0.378 | 1.215(0.788—1.872) | |
rs974336 | AA | 9(4.5) | 3(1.5) | 3.983 | 0.137 | |
AG | 63(31.5) | 74(37) | ||||
GG | 128(64) | 123(61.5) | ||||
AA + AG | 72(36) | 77(38.5) | 0.267 | 0.605 | 0.899(0.599—1.348) | |
rs3217992 | AA | 61(30.5) | 60(30) | 1.021 | 0.600 | |
AG | 101(50.5) | 94(47) | ||||
GG | 38(19) | 46(23) | ||||
AG + GG | 139(69.5) | 140(70) | 0.012 | 0.913 | 0.977(0.637—1.496) | |