Selection bias in clinical stroke trials depending on ability to consent

BMC Neurology

Table 4 Associations of demographic and stroke characteristics in patients able (strictly personal) and unable to consent (legal representative) in a multivariate logistic regression model

	P-value	OR (95% CI)
Pre-stroke living	0.010	2.33 (1.23–4.43)
Admission NIHSS score	0.001	1.22 (1.08–1.38)
Dysphagia	0.018	0.30 (0.11–0.82)
MCA Infarction right	<0.001	0.15 (0.06–0.37)
Discharge BI	0.059	0.98 (0.96–1.00)
Fever during hospitalisation	0.005	3.87 (1.51–9.90)

All values obtained by logistic regression with stepwise backwards exclusion. All predictors showing association of p ≤ 0.1 in univariate analysis were included in the analysis; Abbreviations: NIHSS National Institute of Health Stroke Scale, MCA middle cerebral artery, BI Barthel Index

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