Fig. 1From: Reperfusion therapy in acute ischemic stroke: dawn of a new era?The illustration of the fibrinolytic mechanisms: (a) tissue plasminogen activator (tPA) causes breakdown of the clot, and (b) detailed mechanism of fibrinolysis. Green arrow denotes activation/stimulation, and the red arrow indicates inhibition. tPA = tissue plasminogen activator; UK = Urokinase; PAI = plasminogen activator inhibitorBack to article page