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Table 2 The list of selected features of gene sets for comparison

From: Revealing Alzheimer’s disease genes spectrum in the whole-genome by machine learning

Feature

Source

Description

Gene length

Ensembl [29]

Length of gene in bp

Protein length

UniProt [30]

Length of protein in aa

CDS length

Ensembl

Length of coding sequence in bp

Length of 3’ UTR

Ensembl

Length of the 3′ untranslated region in bp

Length of 5’ UTR

Ensembl

Length of the 5′ untranslated region in bp

Transcript count

Ensembl

Transcript count in the gene

Number of exons

Ensembl

Number of exons in the gene

GC content

Ensembl

GC content (%) of gene

Transmembrane domain

Ensembl

If the gene has a transmembrane domain

Signal domain

Ensembl

If the gene has a signal domain

Paralog

Ensembl

If the gene has a paralog in the human genome