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Table 1 Demographic data

From: The MRZ reaction helps to distinguish rheumatologic disorders with central nervous involvement from multiple sclerosis

Study group

RDwCNS (n = 23)

MS (n = 46)

OIND (n = 48)

Comparison statistics

Sex, Females in %

78.3

78.3

41.7

RDwCNS vs. MS: n.s.

Both groups vs. OIND: p < 0.01.

Mean age in years at the time of LP (range; SD)

44.8

(21–75; 16.8)

43.9

(20–74; 15.6)

51.8

(4–84; 18.4)

All comparisons: n.s.

Disease duration at the time of LP in months (range; SD)

77.0

(0–516; 112.6)

60.5

(0–468; 91.1)

11.6

(0–120; 24.7)

RDwCNS vs. MS: n.s.

Both groups vs. OIND: p < 0.005

  1. RDwCNS Rheumatologic disorders with CNS involvement, MS Multiple sclerosis, OIND Other inflammatory autoimmune neurological diseases [17], LP Lumbar puncture, SD Standard deviation, n.s Not significant