Table 1 Demographic and clinical data of population of patients with acute brain disease, with or without nosocomial infection

Number total

pts

3464 (100%)

198 (5.7%)

3266 (94.3%)

January

pts

327 (9.4%)

7 (3.6%)

310 (9.5%)

February

pts

249 (7.2%)

19 (9.6%)

230 (7.0%)

March

pts

267 (7.7%)

19 (9.6%)

248 (7.6%)

April

pts

305 (8.8%)

13 (6.6%)

292 (8.9%)

May

pts

269 (7.8%)

21 (10.6%)

248 (7.6%)

June

pts

290 (8.4%)

17 (8.6%)

273 (8.4%)

0.660

July

pts

310 (8.9%)

19 (9.6%)

291 (8.9%)

August

pts

274 (7.98%)

12 (6.1%)

262 (8.0%)

September

pts

307 (8.9%)

14 (7.1%)

293 (9.0%)

October

pts

280 (8.1%)

13 (6.6%)

267 (8.2%)

November

pts

291 (8.4%)

17 (8.6%)

274 (8.4%)

December

pts

295 (8.5%)

17 (8.6%)

278 (8.5%)

Age

pts

57.2±15.6

56.3±15.6

0.416

Male

pts

2004 (57.9%)

117 (59.1%)

1887 (57.8%)

0.716

Weight

kg

78.7±17.1

77.6±15.8

0.423

BMI

26.8±5.0

26.8±4.9

0.966

NICU stay

day

15.3±11.7

4.8±5.4

<0.001

Admission

 Primary

pts

746 (21.5%)

47 (23.7%)

699 (21.4%)

 Secondary to 24 h

pts

739 (21.3%)

51 (25.8%)

688 (21.1%)

0.134

 Secondary after 24 h

pts

1979 (57.1%)

100 (50.5%)

1879 (57.5%)

Acute admission

pts

1020 (29.4%)

70 (35.4%)

950 (29.1%)

<0.001

Rehospitalisation

pts

40 (1.22%)

4 (2.0%)

44 (1.3%)

0.331

Diagnoses

 Stroke

pts

1498 (43.2%)

110 (55.6%)

1388 (42.5%)

 Trauma

pts

472 (13.6%)

27 (13.6%)

445 (13.6%)

 Tumour

pts

1078 (31.1%)

33 (16.7%)

1045 (32.0%)

<0.001

 Epilepsy

pts

133 (3.8%)

3 (1.5%)

130 (4.0%)

 Hydrocephalus

pts

119 (3.4%)

13 (6.6%)

106 (3.2%)

 Infection

pts

88 (2.5%)

11 (5.6%)

77 (2.4%)

 Others

pts

75 (2.2%)

1 (0.5%)

74 (2.3%)

 Stroke

pts

<0.001

  Ischemic

pts

580 (16.7%)

21 (10.6%)

559 (17.1%)

  ICH

pts

471 (13.6%)

49 (24.7%)

422 (12.9%)

  SAH

pts

447 (12.9%)

40 (20.2%)

407 (12.5%)

TISS on admission

54.7±1.9

56.0±1.7

<0.001

TISS total

270632.8±231533.1

60415.1±92140..3

<0.001

GCS on admission

11.5±3.5

13.1±3.0

<0.001

APACHE II on admission

15.1±5.5

11.8±5.8

<0.001

GOS on NICU discharge

3.1±1.1

3.9±1.1

<0.001

Mortality in NICU

pts

152 (4.4%)

21 (10.6%)

131 (4.0%)

<0.001

Mortality in NICU

day

16.2±10.4

7.5±5.7

<0.001

CRP on admission

31.7±45.6

17.5±39.1

<0.001

CRP postoperative

30.0±44.4

14.0±33.0

<0.001

CRP 1 day after operation

59.8±56.9

31.6±39.6

<0.001

CRP highest in NICU stay

228.0±122.5

66.1±80.3

<0.001