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Table 9 Nosocomial infections on admission and onset in the NICU

From: Low incidence of multidrug-resistant bacteria and nosocomial infection due to a preventive multimodal nosocomial infection control: a 10-year single centre prospective cohort study in neurocritical care

Parameter

Unit

NI total

NI on admission

NI onset in NICU

p value

Number total

pts

198 (100%)

45 (22.7%)

153 (77.3%)

 

Age

pts

57.2±15.6

53.7±16.9

58.3±15.1

0.086

Male

pts

117(59.1%)

18(40.0%)

63(41.2%)

<0.001

NICU stay

day

15.3±11.7

6.9±7.2

17.7±11.6

<0.001

Diagnoses

 Stroke

pts

110(55.6%)

13(28.9%)

97(63.4%)

 

 Trauma

pts

27(13.6%)

3(6.7%)

24(15.7%)

 

 Tumour

pts

33(16.7%)

13(28.9%)

20(13.1%)

 

 Epilepsy

pts

3(1.5%)

0(0.0%)

3(2.0%)

<0.001

 Hydrocephalus

pts

13(6.6%)

7(15.6%)

6(3.9%)

 

 Infection

pts

11(5.6%)

9(20.0%)

2(1.3%)

 

 Others

pts

1(0.5%)

0(0.0%)

1(0.7%)

 

TISS on admission

 

54.7±1.9

56.0±179

54.3±1.8

<0.001

TISS total

 

270632.8±231533.1

111173.7±231533.1

309492.6±234698.9

<0.001

GCS on admission

 

11.5±3.5

12.0±3.3

11.3±3.5

0.234

APACHE II on admission

 

15.1±5.5

13.6±5.4

15.4±5.5

0.099

GOS on NICU discharge

 

3.1±1.1

3.5±1.2

3.0±1.1

0.015

Mortality in NICU

pts

21(10.6%)

3(6.7%)

18(11.8%)

0.329

Operation

pts

151(76.3%)

37(82.2%)

114(74.5%)

0.285

Airways

pts

112(56.6%)

16(35.6%)

96(62.7%)

0.001

Mechanical ventilation

pts

87(43.9%)

7(15.6%)

80(52.3%)

<0.001

Artery catheter

pts

90(45.5%)

6(13.3%)

84(54.9%)

<0.001

Central venous catheter

pts

64(32.3%)

11(24.4%)

53(34.6%)

0.199

Lumbar drainage

pts

36(18.2%)

5(11.1%)

31(20.3%)

0.162

Ventricular drainage

pts

21(10.6%)

3(6.7%)

18(11.8%)

0.329

Corticoids

pts

47(23.7%)

11(24.4%)

36(23.5%)

0.899

Transfusions

pts

41(20.7%)

5(11.1%)

36(23.5%)

0.071

Ulcer prophylaxis

pts

134(67.7%)

27(60.0%)

107(69.9%)

0.210

Diabetes Mellitus

pts

22(11.1%)

3(6.7%)

19(12.4%)

0.280

Antibiotic prophylaxis

pts

127(64.1%)

23(51.1%)

104(68.0%)

0.038

Antibiotic therapy

pts

169(85.4%)

28(62.2%)

141(92.2%)

<0.001

ESBL

pts

6(3.0%)

1(2.2%)

5(3.3%)

0.719

MRSA

pts

7(3.5%)

1(2.2%)

6(3.9%)

0.587

One infection

pts

189(95.5%)

45(100.0%)

144(94.1%)

 

Two infections

pts

8(4.0%)

0(0.0%)

8(5.2%)

0.250

Three infections

pts

1(0.5%)

0(0.0%)

1(0.7%)

 

 Bloodstream

pts

23(11.6%)

1(2.2%)

22(14.4%)

0.025

   Vascular catheter

pts

14(7.1%)

1(2.2%)

13(8.5%)

0.149

 Respiratory

pts

63(31.8%)

3(6.7%)

60(39.2%)

< 0.001

  VAP

pts

34(17.2%)

1(2.2%)

33(21.6%)

0.002

 Urinary

pts

35(17.7%)

5(11.1%)

30(19.6%)

0.189

  Urinary catheter

pts

33(16.7%)

5(11.1%)

25(16.3%)

0.255

 Wound without operation

pts

2(1.0%)

1(2.2%)

1(0.7%)

0.355

 Wound with operation

pts

70(35.4%)

35(77.8%)

35(22.9%)

<0.001

  Wound complication

   Liquorrhoea

pts

14(7.1%)

7(15.6%)

7(4.6%)

0.012

   Dehiscence

pts

11(5.6%)

9(20.0%)

2(1.3%)

<0.001

   Fistula

pts

6(3.6%)

3(6.7%)

3(2.0%)

0.105

  1. NICU neurointensive care unit, TISS Therapeutic Intervention Scoring System, GCS Glasgow Coma Scale, APACHE Acute Physiology and Chronic Health Evaluation, GOS Glasgow Outcome Scale, ESBL Extended spectrum beta-lactamase, MRSA Methicillin-resistant Staphylococcus aureus, VAP ventilator associated pneumonia