Prognostic models for complete recovery in ischemic stroke: a systematic review and meta-analysis

Jampathong, Nampet; Laopaiboon, Malinee; Rattanakanokchai, Siwanon; Pattanittum, Porjai

doi:10.1186/s12883-018-1032-5

BMC Neurology

Table 1 Characteristics of prognostic models

From: Prognostic models for complete recovery in ischemic stroke: a systematic review and meta-analysis

First author (year)	Setting	Study period	Study design	Model No.	Type of model	Definition of outcome	Participants				No. of complete recovery	Events per variable	Duration of follow-up
First author (year)	Setting	Study period	Study design	Model No.	Type of model	Definition of outcome	n	Age	Male	NIHSS score	No. of complete recovery	Events per variable	Duration of follow-up
Johnston (2000)	America	May 1993 - Dec 1994	Cohort	1	Internal	BI ≥ 95	222	68.7^b	–	10 (5, 15)^a	125	125	90 days
				2								21
				3								18
				4		GOS = 1	222	68.7^b	–	10 (5, 15)^a	108	108
				5								18
				6								16
Johnston (2003)	America	–	Cohort	3	External	BI ≥ 95	199	67 (59,74)^a	59%	15(10, 20)^a	78	12	90 days
Johnston (2003)	America	–	Cohort	6	External	GOS = 1	199	67 (59,74)^a	59%	15(10, 20)^a	62	9	90 days
Johnston (2002)	America	May 1993 - Dec 1994	Cohort	7	Internal	BI ≥ 95	206	69 (12)^b	–	10 (5, 16)^a	92	92	90 days
				8								92
				9								46
				10		GOS = 1	206	69 (12)^b	–	10 (5, 16)^a	99	99
				11								99
				12								50
Johnston (2007)	America	–	Cohort	13	Development	BI ≥ 95	382	69 (58, 77)^a	53.9%	14 (10, 18)^a	123	25	90 days
		May 2000 & Aug 2005		13	External		266	70 (58, 78)^a	53.0%	5 (3, 10)^a	167	34
		–		14	Development		382	69 (58, 77)^a	53.9%	14 (10, 18)^a	123	16
		May 2000 & Aug 2005		14	External		266	70 (58, 78)^a	53.0%	5 (3, 10)^a	167	21
		–		15	Development	mRS ≤ 1	382	69 (58, 77)^a	53.9%	14 (10, 18)^a	75	15
		May 2000 & Aug 2005		15	External		266	70 (58, 78)^a	53.0%	5 (3, 10)^a	148	30
		–		16	Development		382	69(58, 77)^a	53.9%	14 (10, 18)^a	75	10
		May 2000 & Aug 2005		16	External	mRS ≤ 1	266	70 (58, 78)^a	53.0%	5 (3, 10)^a	148	19	90 days
Weimar (2002)	Germany	1998 - 1999	Cohort	17	Development	BI ≥ 95	1743	68.1 (12.7)^b	59.2%	6.9 (6.2)^b	1021	102	100 days
German Stroke Study Collaboration (2004)	Germany	Feb 2001 - Mar 2002	Cohort	17	External	BI ≥ 95	1470	67.9 (12.4)^b	57.3%	6.4 (6.0)^b	831	76	100 days
Weimar (2004)	Germany	–	Cohort	18	Development	BI ≥ 95	1079	67.0 (12.3)^b	60.5%	–	644	322	100 days
Weimar (2004)	Germany	Feb 2001 - Mar 2002	Cohort		External	BI ≥ 95	1307	68.2 (12.5)^b	56.5%	7.6 (6.9)^b	722	361	100 days
Konig (2008)	–	–	Cohort		External	BI ≥ 95	4441	68.8 (12.3)^b	55.8%	13.4 (6.5)^b	1970	985	90 days
Schiemanck (2006)	Netherland	1999 - 2001	Cohort	19	Development	BI ≥ 19	75	63 (15)^b	47%	11 (6)^b	33	17	365 days
Schiemanck (2006)	Netherland	1999 - 2001	Cohort	20	Development	BI ≥ 19	75	63 (15)^b	47%	11 (6)^b	33	7	365 days
Patti (2016)	America	2013 - 2014	Cohort	21	Development	mRS ≤ 1	414	70 (50, 69)^a	50%	5 (2, 13)^a	230	77	90 days
				22			204	–	–	–	–	–
				23			210	–	–	–	–	–

^aMedian (25th–75th percentile); ^b Mean (SD); − indicates not stated

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