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Table 1 Comparison of PD patients with/without constipation

From: A survey of subjective constipation in Parkinson’s disease patients in shanghai and literature review

Item PD with constipation PD without constipation Test value P value
Number of case N = 145 N = 123 / /
Male/Femaleb 83/62 66/57 χ2 = 0.346 0.622
Age (year)a 69.49 ± 10.06 67.69 ± 9.80 t = − 1.472 0.142
BMIa 22.69 ± 3.03 22.63 ± 2.77 t = 0.157 0.876
Life Style
 Moderate exerciseb 33(22.76%) 43(34.96%) χ2 = 4.876 <  0.05
 Moderate drinkingb 80(55.17%) 85(69.11%) χ2 = 5.460 <  0.05
 Smokingb 13(8.97%) 8(6.50%) χ2 = 0.558 >  0.05
Parkinsonism clinical characteristic
Age of motor onset (year)a 63.75 ± 9.51 62.67 ± 10.45 t = −0.873 0.383
Phenotype of onsetb
 tremor-dominant 86(59.31%) 88(71.54%) χ2 = 5.109 <  0.05
 Bradykinetic-rigid dominant 54(37.24%) 30(24.39%)
 others 5(3.45%) 5(4.07%)
Disease duration (year)a 6.29 ± 4.95 5.13 ± 4.65 t = −1.946 0.053
Dose of levodopa (mg/d)a 581.11 ± 345.05 467.60 ± 327.54 t = −2.589 0.010
LED (mg/d)a 705.02 ± 417.86 518.87 ± 378.51 t = −3.576 0.000
Daily levodopa/kg (mg/kg)a 9.11 ± 6.75 7.94 ± 6.00 t = −1.399 0.163
UPDRS scorea 43.91 ± 25.74 35.86 ± 21.14 t = −2.783 0.006
UPDRSIII scorea 25.82 ± 15.45 22.61 ± 14.81 t = −1.708 0.089
H-Ya 2.29 ± 0.87 2.16 ± 1.41 t = −0.900 0.369
NMSSa 52.77 ± 42.32 31.70 ± 28.18 t = − 4.655 0.000
MMSEa 26.38 ± 3.86 26.65 ± 3.97 t = −0.553 0.581
PDSSa 111.48 ± 26.15 119.17 ± 25.60 t = −2.222 0.027
HAMAa 11.89 ± 8.80 9.42 ± 7.60 t = 2.782 0.006
HAMDa 15.37 ± 11.38 12.05 ± 10.03 t = 2.361 0.019
PDQ-39a 35.82 ± 28.23 25.50 ± 24.18 t = −3.089 0.002
CCS 13.16 ± 5.65
  1. Moderate exercise [12]: For adult, daily total physical activity is equivalent to at least 6000 steps accumulatively. Moderate drinking [13]: 1.5-2 L/day
  2. LED: Levodopa equivalent doses were calculated as 100 mg L-dopa = 10 mg bromocriptine = 50 mg piribedil = 1 mg prampexole [5]
  3. Statistial significance (p< 0.05) in italics
  4. astatistic with t-test
  5. bstatistic with χ2 test