Table 1 Comparison of PD patients with/without constipation

Number of case

N = 145

N = 123

/

/

Male/Female^b

83/62

66/57

χ² = 0.346

0.622

Age (year)^a

69.49 ± 10.06

67.69 ± 9.80

t = − 1.472

0.142

BMI^a

22.69 ± 3.03

22.63 ± 2.77

t = 0.157

0.876

 Moderate exercise^b

33(22.76%)

43(34.96%)

χ² = 4.876

<  0.05

 Moderate drinking^b

80(55.17%)

85(69.11%)

χ² = 5.460

<  0.05

 Smoking^b

13(8.97%)

8(6.50%)

χ² = 0.558

>  0.05

Age of motor onset (year)^a

63.75 ± 9.51

62.67 ± 10.45

t = −0.873

0.383

 tremor-dominant

86(59.31%)

88(71.54%)

χ² = 5.109

<  0.05

 Bradykinetic-rigid dominant

54(37.24%)

30(24.39%)

 others

5(3.45%)

5(4.07%)

Disease duration (year)^a

6.29 ± 4.95

5.13 ± 4.65

t = −1.946

0.053

Dose of levodopa (mg/d)^a

581.11 ± 345.05

467.60 ± 327.54

t = −2.589

0.010

LED (mg/d)^a

705.02 ± 417.86

518.87 ± 378.51

t = −3.576

0.000

Daily levodopa/kg (mg/kg)^a

9.11 ± 6.75

7.94 ± 6.00

t = −1.399

0.163

UPDRS score^a

43.91 ± 25.74

35.86 ± 21.14

t = −2.783

0.006

UPDRSIII score^a

25.82 ± 15.45

22.61 ± 14.81

t = −1.708

0.089

H-Y^a

2.29 ± 0.87

2.16 ± 1.41

t = −0.900

0.369

NMSS^a

52.77 ± 42.32

31.70 ± 28.18

t = − 4.655

0.000

MMSE^a

26.38 ± 3.86

26.65 ± 3.97

t = −0.553

0.581

PDSS^a

111.48 ± 26.15

119.17 ± 25.60

t = −2.222

0.027

HAMA^a

11.89 ± 8.80

9.42 ± 7.60

t = 2.782

0.006

HAMD^a

15.37 ± 11.38

12.05 ± 10.03

t = 2.361

0.019

PDQ-39^a

35.82 ± 28.23

25.50 ± 24.18

t = −3.089

0.002

CCS

13.16 ± 5.65

–

–

–