Table 1 Characteristics and laboratory values at baseline
n | Study population Mean (SD) unless otherwise stated | Normal range | |
|---|---|---|---|
Female gender (n [%]) | 53 | 23 (43.4) | |
Age (years) | 53 | 36.2 (11.3) | |
Age at onset (years) | 52 | 30.4 (12.5) | |
Onset to diagnosis (years) | 52 | 5.6 (6.6) | |
Presence of Kayser-Fleischer ring (n [%]) | 53 | 44 (83.0) | |
Ceruloplasmin (mg/dL) | 53 | 13.7 (6.3) | 25–45 |
Serum copper (μg/dL) | 53 | 62.0 (17.8) | 70–140 |
Urinary copper (μg/24 h) | 53 | 128 (142) | < 50 |
Non-ceruloplasmin-bound copper (μmol/L) | 53 | 3.4 (2.0) | a |
Alanine aminotransferase (IU/L) | 53 | 38 (43) | < 41 |
Aspartate aminotransferase (IU/L) | 53 | 36 (21) | < 40 |
Gamma-glutamyltransferase (IU/L) | 52 | 70 (57) | < 42 |
International normalized ratio | 52 | 1.3 (0.2) | 0.8–1.2 |
Bilirubin (mg/dL) | 53 | 1.1 (0.6) | < 1 |
Serum albumin (g/dL) | 47 | 4.0 (0.7) | 3.5–5.0 |