Table 1 Clinical and demographic features
MS (n = 66) | HC (n = 16) | p-value | |
|---|---|---|---|
Age, mean (SD) | 43.4 (12) | 46.8 (9) | 0.32 |
Gender, n(%) | 0.21 | ||
Females | 48 (72.7) | 9 (56.3) | |
Males | 18 (27.3) | 7 (43.7) | |
Education (years), median (range) | 13 (5-21) | 13 (8-19) | 0.096 |
Disease duration, mean; median (range) | 10.8; 8.5 (0-34) | ||
EDSS, median (range) | 2 (0-7.5) | ||
NBV, mean (SD) | 1473.5 (81.9) | 1519.6 (38.4) | 0.006^ |
NWV, mean (SD) | 694 (39.9) | 728.1 (19.1) | 0.003^ |
NGV, mean (SD) | 777.7 (72) | 791.5 (33.1) | 0.14^ |
p-NGV, mean (SD) | 609.6 (52.1) | 616.2 (28.7) | 0.11^ |
SDMT, mean (SD) | 45.1 (12.3) | 53.3 (8.4) | 0.037* |
CVLT-II, mean (SD) | 41.6 (10.3) | – | |
BVMT-R, mean (SD) | 47.6 (10.8) | – | |
RNFL, mean (SD) | 93.8 (10.7) | 101.8 (9.9) | 0.014 |
TEMP-RNFL, mean (SD) | 63.3 (11) | – | |
PMB-RNFL, mean (SD) | 49.6 (9.4) | – |