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Table 1 Clinical and demographic features

From: A cross-sectional and longitudinal study evaluating brain volumes, RNFL, and cognitive functions in MS patients and healthy controls

  MS (n = 66) HC (n = 16) p-value
Age, mean (SD) 43.4 (12) 46.8 (9) 0.32
Gender, n(%)    0.21
 Females 48 (72.7) 9 (56.3)  
 Males 18 (27.3) 7 (43.7)  
Education (years), median (range) 13 (5-21) 13 (8-19) 0.096
 Disease duration, mean; median (range) 10.8; 8.5 (0-34)   
 EDSS, median (range) 2 (0-7.5)   
 NBV, mean (SD) 1473.5 (81.9) 1519.6 (38.4) 0.006^
 NWV, mean (SD) 694 (39.9) 728.1 (19.1) 0.003^
 NGV, mean (SD) 777.7 (72) 791.5 (33.1) 0.14^
 p-NGV, mean (SD) 609.6 (52.1) 616.2 (28.7) 0.11^
 SDMT, mean (SD) 45.1 (12.3) 53.3 (8.4) 0.037*
 CVLT-II, mean (SD) 41.6 (10.3)  
 BVMT-R, mean (SD) 47.6 (10.8)  
 RNFL, mean (SD) 93.8 (10.7) 101.8 (9.9) 0.014
 TEMP-RNFL, mean (SD) 63.3 (11)  
 PMB-RNFL, mean (SD) 49.6 (9.4)  
  1. ^ - linear regression model adjusted for Age; *linear regression model adjusted for education
  2. MRI measures (NBV, NWV, NGV, p-NGV) are expressed in ml
  3. Cognitive measures (SDMT, CVLT-II, BVMT-R) are expressed in T score