Differentiation of neuropsychological features between posterior cortical atrophy and early onset Alzheimer’s disease

Table 3 Neuropsychological test scores for samples of patients diagnosed with posterior cortical atrophy (PCA; n = 18) and early onset Alzheimer’s disease (EOAD; n = 20)

Neuropsychological tests	PCA	EOAD	P value
MMSE score (30)	14 (8.8)	13 (9)	> 1.000^a
MoCA score (30)	9.8 (5.7)	11.3 (5.9)	> 1.000^b
CDR - SOB (18)	6 (5.1)	6.5 (4.5)	> 1.000^a
Attention & working memory
Digit span forward (11)	7 (1.5)	7 (2)	> 1.000^a
Digit span backward (9)	3 (1)	3 (1)	.898^a
Executive function
Trail Making Test A Score (24)	0 (11)	17.5 (24)	.087^a
Trail Making Test B Score (24)	0 (0)	0 (10.5)	.794^a
Language
Boston naming test (30)	13.5 (12.8)	17 (10.5)	.375^a
Verbal fluency	9.6 (3.6)	8.9 (3.3)	> 1.000^b
Visuo-constructive function
Rey-Osterreith complex figure copy (36)	3.5 (4.6)	17.8 (16.9)	.011^a
Memory
AVLT-immediate (45)	11.6 (5.3)	11.6 (7.0)	> 1.000^b
AVLT-delay (15)	0 (2.3)	0 (1)	> 1.000^a
AVLT-clue (15)	2 (3)	3 (5.5)	> 1.000^a
AVLT-recognized (15)	2.5 (4.3)	3.5 (5.5)	> 1.000^a
Calculation (8)	0.5 (2)	2 (3.75)	.141^a
Writing test (21)	1.5 (15.5)	21 (6.5)	.002^a
Reading test (19)	13.3 (8.2)	19 (3.5)	.002^a
Visual-spatial
Bell cancellation (35)	7 (10)	19.5 (22.5)	.018^a
Overlapping figure (20)	6.5 (6.3)	16.5 (5)	.002^a
Navon figure (12)	5.5 (7.3)	12 (2)	.001^a
Visual-perceptual
Matching test (10)	7 (3)	10 (2.75)	.004^a
Cookie theft picture (15)	7.5 (6.5)	9.5 (4)	.044^a

Data are shown as median (IQR) or mean (SD). Numbers in parentheses next to the test name are maximum possible scores. MMSE, Mini-Mental State Examination; MoCA, Montreal Cognitive Assessment; CDR-SOB, Clinical Dementia Rating-Sum of Box; AVLT, Auditory Verbal Learning Test
^aKruskal-Wallis one-way ANOVA followed by post-hoc test
^bANOVA followed by Bonferroni test

ISSN: 1471-2377