Fig. 2

Regression coefficients and significance for clinical variables and white matter impairments. The increased MD values in the right ACR negatively correlated with CD4⁺/CD8⁺ ratios. The increased AD values in the left PCR negatively correlated with CD4⁺/CD8⁺ ratios. The increased AD values in the right ALIC positively correlated with viral load and CD4⁺/CD8⁺ ratios

Note: bar: P value; *: p < 0.1; **: p < 0.05; red circle: regression coefficients of MD; black square: regression coefficients of AD.

MD, mean diffusivity; AD, axial diffusivity; GCC, genu of corpus callosum; BCC, body of corpus callosum; SCC, splenium of corpus callosum; ACR, anterior corona radiata; SCR, superior corona radiata; ALIC, anterior limb of internal capsule; EC, external capsule; RIC, retrolenticular part of internal capsule; PCR, posterior corona radiata; PTR, posterior thalamic radiation; SS, sagittal stratum; SLF, superior longitudinal fasciculus. l, left; r, right; VL, viral load; DI, duration of infection.