Table 1 Demographic and Clinical Data of PD Patients in APF Group and NPF Group
Patients with PD | |||
|---|---|---|---|
Clinical demographics | APF group, n = 25 | NPF group, n = 25 | P-value |
Age (years) | 63 ± 11 | 62 ± 7 | 0.828 |
Sex (male/female) | 13/12 | 14/11 | 0.777 |
GMV | 546.0 ± 75.0 | 578.6 ± 57.8 | 0.098 |
WMV | 432.1 ± 57.3 | 432.6 ± 45.4 | 0.871 |
TIV | 1337.6 ± 134.4 | 1364.6 ± 133.7 | 0.441 |
Pulmonary function parameters | |||
FVC (% pred) | 85.4 ± 20.4 | 99.8 ± 13.6 | 0.030* |
FEV1 (% pred) | 84.1 ± 19.1 | 105.9 ± 14.0 | < 0.001* |
FEV1/FVC | 79.7 ± 9.0 | 86.7 ± 4.9 | < 0.001* |
MEF 50 (%) | 63.2 ± 22.9 | 98.7 ± 14.2 | < 0.001* |
SpO2 (%) | 94.5 ± 3.4 | 94.3 ± 2.7 | 0.756 |
Disease severity scale | |||
UPDRS I | 4.1 ± 3.6 | 3.3 ± 2.5 | 0.435 |
UPDRS II | 12.5 ± 9.7 | 9.7 ± 5.6 | 0.311 |
UPDRS III | 28.8 ± 23.0 | 23.5 ± 11.8 | 0.396 |
UPDRS total | 45.4 ± 35.1 | 36.5 ± 18.8 | 0.357 |
Modified H & Y | 2.2 ± 1.3 | 1.8 ± 0.9 | 0.276 |
S & E | 78.3 ± 20.8 | 86.7 ± 11.1 | 0.128 |
Inflammatory markers | |||
TBARS (µM/L) | 13.9 ± 5.1 | 13.1 ± 5.1 | 0.520 |
Thiol (µM/L) | 1.3 ± 0.5 | 1.5 ± 0.4 | 0.360 |
ICAM-1 | 215.1 ± 65.6 | 195.3 ± 75.8 | 0.514 |
P-selectin | 100.5 ± 18.1 | 97.0 ± 13.0 | 0.314 |
E-selectin | 42.6 ± 18.3 | 34.0 ± 18.0 | 0.243 |
CD133+CD34+ (%) | 18.4 ± 16.1 | 27.7 ± 27.9 | 0.195 |
KDR+CD34+ (%) | 3.5 ± 4.5 | 3.2 ± 4.7 | 0.943 |