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Table 2 Univariable and multivariable predictors of unfavorable outcome (mRS > 2)

From: Hemoglobin concentration does not impact 3-month outcome following acute ischemic stroke

 

Univariable Analysisa

Multivariable analysisb

OR (95% CI)

P Value

Adjusted OR (95% CI)

P value

Age

1.02 (1.01–1.04)

< 0.001

1.02 (1.01–1.04)

0.001

NIHSS score

1.26 (1.19–1.33)

< 0.001

1.30 (1.23–1.39)

< 0.001

IV alteplase use

0.84 (0.42–1.61)

0.59

0.19 (0.07–0.46)

< 0.001

Charlson Comorbidity Index

1.30 (1.17–1.44)

< 0.001

1.25 (1.11–1.41)

< 0.001

Nadir Hb

0.82 (0.76–0.89)

< 0.001

0.99 (0.89–1.10)

0.84

Delta Hb

1.40 (1.20–1.60)

< 0.001

  

Anemia during hospitalization

1.60 (1.15–2.33)

0.006

  

Red blood cell transfusion

2.67 (1.21–6.31)

0.013

1.45 (0.49–4.40)

0.50

  1. Abbreviations: CI Confidence interval, OR Odds ratio, Hb Hemoglobin
  2. aOdds ratios are per unit change for continuous variables (Age,y; NIHSS score; Charlson Comorbidity Index; Nadir Hb, g/dl; Delta Hb, g/dl; Body Mass Index)
  3. bOnly one multivariable model shown here. Results for models with other Hb indices shown in Table 3.