Fig. 1From: Highly selective SGLT2 inhibitor dapagliflozin reduces seizure activity in pentylenetetrazol-induced murine model of epilepsyEffect of dapagliflozin on epileptiform activity on EEG as measured by spike percentage for PTZ–induced seizures in rats. When compared to the A2 arm in which no dapagliflozin (DGF) was administered, intraperitoneal (IP) dapagliflozin at 75 mg/kg and 150 mg/kg were able to significantly reduce mean EEG spike percentage by over 3 times, with p–value of < 0.0001, in rats treated with 35 mg/kg of IP pentylenetetrazol (PTZ). The ± range represents the standard deviation (SD) from the meanBack to article page