From: Highly selective SGLT2 inhibitor dapagliflozin reduces seizure activity in pentylenetetrazol-induced murine model of epilepsy
Arm
Intervention
Recovery time (seconds)
A1
Saline control arm
0 ± 0.0
A2
PTZ at 70 mg/kg and saline
565.8 ± 12.7
A3
PTZ at 70 mg/kg and dapaglifozin at 75 mg/kg
483.3 ± 35.2*
A4
PTZ at 70 mg/kg and dapaglifozin at 150 mg/kg
368 ± 24.9*