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Table 1 Baseline data for patients and s-IGF-I in each of the quintiles of changing s-IGF-I (ΔIGF-I-q1–5)

From: Altered levels of circulating insulin-like growth factor I (IGF-I) following ischemic stroke are associated with outcome - a prospective observational study

Parameter Unit Value
n   354
Age at index ischemic stroke Years (SD) 55.4 (11)
Sex Missing (N) 229/125
Male/female (fraction) 0.65
Diabetes Yes (N/fraction) 67 (0.19)
Missing (N) 0
Hypertension Yes (N/fraction) 188 (0.53)
Missing (N) 0
Current smoking Yes (N/fraction) 136 (0.38)
Missing (N) 0
LDL level (ng/nL) Mean (SD) 3.3 (1.0)
Missing (N) 27
P-glucose (acute) Mean (SD) 6.5 (2.64)
Missing (N) 8
P-glucose (3 m) Mean (SD) 6.03 (2.29)
Missing (N) 8
Stroke severity (NIHSS) Mean (20, 80%) 5.3 (0.7, 10.2)
Missing (N) 0
Stroke outcome (mRS) 3 m Mean(SD) 1.85 (1.06)
Missing (N) 5
Stroke outcome (mRS) 2 yr mRS (SD) 1.77 (1.32)
Missing (N) 2
Dead (3-24 m) Yes (n/fraction) 9 (0.025)
Missing (N) 0
s-IGF-I (acute) ng/mL (SD) 172.8 (62.9)
Missing (N) 0
s-IGF-I (3 m) ng/mL (SD) 152.7 (55.7)
Missing (N) 0
ΔIGF-I (ng/mL), all data ng/mL (SD) 20.2 (51.0)
Missing (N) 0
Quintile of ΔIGF-I:   ΔIGF-I (ng/mL) s-IGF-I acute (ng/mL) Change (%)
  ΔIGF-I-q1 (SD) − 48.3 (48.0) 146.5 (53.7) incr. 33.0
  (N) 71 71 71
  ΔIGF-I-q2 (SD) 1.6 (5.8) 145.4 (44.6) decr. 1.10
  (N) 72 72 72
  ΔIGF-I-q3 (SD) 20.8 (5.7) 152.5 (56.0) decr 13.5
  (N) 71 71 71
  ΔIGF-I-q4 (SD) 42.5 (7.2) 178.9 (45.9) decr 23.6
  (N) 70 70 70
  ΔIGF-I-q5 (SD) 85.9 (28.0) 240.5 (57.6) decr 35.7
  (N) 70 70 70
  1. Absolute ΔIGF-I (ng/mL) represents a subtraction of acute s-IGF-I by 3-month s-IGF-I. A negative numerical value represents an increase from the acute to 3-month time point, and a positive numerical value represents a decrease. Modified Rankin scale (mRS), low density lipoprotein (LDL), National Institutes of Health Stroke Scale (NIHSS). An extended version of the table with a comparison to data presented in 2011 is found in Additional file 2: Table S1