Table 1 Baseline characteristics and scores

Age, years

N = 128

N = 35

N = 71

 Mean (SD)

41.5 (11.3)

40.4 (11.8)

41.3 (10.7)

 Median (range)

41.0 (19–70)

41.0 (19–61)

41.0 (19–65)

Gender, n (%)

N = 128

N = 35

N = 71

 Women

91 (71.1)

21 (60.0)

53 (74.7)

 Men

37 (28.9)

14 (40.0)

18 (25.4)

Diagnosis, n (%)

N = 128

N = 35

N = 71

 RRMS

114 (89.1)

31 (88.6)

62 (87.3)

 CIS

14 (10.9)

4 (11.4)

9 (12.7)

Duration of disease, months

N = 113

N = 32

N = 61

 Mean (SD)

43.0 (71.6)

30.9 (63.8)

45.6 (74.3)

 Median (range)

6.9 (0.1–315.1)

6.9 (0.3–262.3)

6.3 (0.1–315.1)

EDSS, median (range)

N = 128

N = 35

N = 71

2.0 (0–5)

2.0 (0–5)

2.0 (0–5)

MFIS

N = 122

N = 35

N = 71

 Mean (SD)

32.38 (20.33)

20.20 (15.24)

39.38 (18.78)

 Median (range)

34.0 (0.0–76.0)

18.0 (0.0–51.0)

43.0 (2.0–76.0)

SF-36 physical component score

N = 113

N = 33

N = 67

 Mean (SD)

44.56 (11.35)

50.86 (8.37)

41.80 (11.41)

 Median (range)

46.53 (16.50–64.06)

53.00 (22.67–64.06)

41.21 (16.50–60.67)

SF-36 mental component score

N = 113

N = 33

N = 67

 Mean (SD)

41.74 (13.28)

47.84 (9.98)

38.27 (13.31)

 Median (range)

44.39 (12.44–63.82)

50.96 (22.76–63.82)

39.54 (12.44–59.53)

HADS-D

N = 128

N = 35

N = 71

 HADS-D ≥ 8, n (%)

29 (22.66)

2 (5.71)

25 (35.21)

HADS-A

N = 128

N = 35

N = 71

 HADS-A ≥ 8, n (%)

41 (32.03)

4 (11.43)

32 (45.07)

ESS

N = 118

N = 35

N = 68

 Mean (SD)

8.03 (4.54)

6.69 (4.26)

8.88 (4.71)

 Median (range)

8.0 (0.0–16.0)

6.0 (0.0–14.0)

9.0 (1.0–16.0)