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Table 1 Baseline characteristics and scores

From: Sleep quality, daytime sleepiness, fatigue, and quality of life in patients with multiple sclerosis treated with interferon beta-1b: results from a prospective observational cohort study

Characteristic All Patients Good sleepers (PSQI< 5) Poor sleepers (PSQI≥5)
Age, years N = 128 N = 35 N = 71
 Mean (SD) 41.5 (11.3) 40.4 (11.8) 41.3 (10.7)
 Median (range) 41.0 (19–70) 41.0 (19–61) 41.0 (19–65)
Gender, n (%) N = 128 N = 35 N = 71
 Women 91 (71.1) 21 (60.0) 53 (74.7)
 Men 37 (28.9) 14 (40.0) 18 (25.4)
Diagnosis, n (%) N = 128 N = 35 N = 71
 RRMS 114 (89.1) 31 (88.6) 62 (87.3)
 CIS 14 (10.9) 4 (11.4) 9 (12.7)
Duration of disease, months N = 113 N = 32 N = 61
 Mean (SD) 43.0 (71.6) 30.9 (63.8) 45.6 (74.3)
 Median (range) 6.9 (0.1–315.1) 6.9 (0.3–262.3) 6.3 (0.1–315.1)
EDSS, median (range) N = 128 N = 35 N = 71
  2.0 (0–5) 2.0 (0–5) 2.0 (0–5)
MFIS N = 122 N = 35 N = 71
 Mean (SD) 32.38 (20.33) 20.20 (15.24) 39.38 (18.78)
 Median (range) 34.0 (0.0–76.0) 18.0 (0.0–51.0) 43.0 (2.0–76.0)
SF-36 physical component score N = 113 N = 33 N = 67
 Mean (SD) 44.56 (11.35) 50.86 (8.37) 41.80 (11.41)
 Median (range) 46.53 (16.50–64.06) 53.00 (22.67–64.06) 41.21 (16.50–60.67)
SF-36 mental component score N = 113 N = 33 N = 67
 Mean (SD) 41.74 (13.28) 47.84 (9.98) 38.27 (13.31)
 Median (range) 44.39 (12.44–63.82) 50.96 (22.76–63.82) 39.54 (12.44–59.53)
HADS-D N = 128 N = 35 N = 71
 HADS-D ≥ 8, n (%) 29 (22.66) 2 (5.71) 25 (35.21)
HADS-A N = 128 N = 35 N = 71
 HADS-A ≥ 8, n (%) 41 (32.03) 4 (11.43) 32 (45.07)
ESS N = 118 N = 35 N = 68
 Mean (SD) 8.03 (4.54) 6.69 (4.26) 8.88 (4.71)
 Median (range) 8.0 (0.0–16.0) 6.0 (0.0–14.0) 9.0 (1.0–16.0)
  1. Subgroups of good sleepers (PSQI< 5) and poor sleepers (PSQI≥5) do not add up to N = 128 (100%) due to missing PSQI baseline values
  2. PSQI Pittsburgh Sleep Quality Index, SD standard deviation, RRMS relapsing-remitting multiple sclerosis, CIS clinically isolated syndrome, EDSS Expanded Disability Status Scale, MFIS Modified Fatigue Impact Scale, SF-36 Short Form 36, HADS Hospital Anxiety and Depression Scale, ESS Epworth Sleepiness Scale