Intracranial pressure responsiveness to positive end-expiratory pressure is influenced by chest wall elastance: a physiological study in patients with aneurysmal subarachnoid hemorrhage

Table 2 Patients characteristics at study entry

	All patients (n = 30)	Responders (n = 15)	Non-responders (n = 15)	p ^*
Age (years)	55 (37–66)	66 (42–73)	42 (37–57)	0.045
Male	21 (70)	10 (67)	11 (73)	0.500
BMI (kg/m²)	22.8 (22.0–24.2)	22.0 (21.2–23.6)	23.6 (22.0–24.2)	0.039
GCS	5.5 (4.0–6.3)	5.0 (4.0–7.0)	6.0 (5.0–6.0)	0.513
SAPS II	49.5 (46.3–54.6)	49.7 (44.0–57.0)	49.0 (47.0–54.0)	0.400
MV duration (days)^a	1.0 (1.0–2.0)	1.0 (1.0–2.0)	2.0 (1.0–2.0)	0.345
ARDS diagnosis	6 (20)	4 (27)	2 (13)	0.361
PaO₂	105.5 (78.0–153.5)	95.0 (76.7–130.0)	129.0 (78.4–168.0)	0.242
PaO₂/FiO₂	264 (180–384)	274 (156–325)	323 (196–420)	0.144
PaCO₂ (mmHg)	35.3 (32.6–36.7)	35.4 (32.7–38.1)	35.1 (30.9–36.1)	0.307

Data are presented as median (interquartile range) for continuous variables and counts (percentages) for categorical variables
ARDS acute respiratory distress syndrome, BMI body mass index, GCS Glasgow Coma Scale, MV mechanical ventilation, SAPS II Simplified Acute Physiology Score II
^*p value in comparison between the responder and non-responder group
^aMV duration before enrolment

ISSN: 1471-2377