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Fig. 7 | BMC Neurology

Fig. 7

From: Targeting the Notch1 oncogene by miR-139-5p inhibits glioma metastasis and epithelial-mesenchymal transition (EMT)

Fig. 7

MiR-139-5p inhibited glioma xenograft growth, metastasis and EMT in vivo and prolonged survival. (a and b) Luminescence imaging for miR-139-5p–treated U87-luc tumours versus scramble-treated controls. (c) Kaplan-Meier survival curves indicating that mice transfected with miR-139-5p showed a significantly better outcome than the miR-Scr-treated group (*P < 0.05). (d) Notch1, E-cadherin, N-cadherin, Fibronectin and Vimentin expression after transfecting miR-139-5p in tumour sections following IHC analysis. (× 100 magnification)

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BMC Neurology

ISSN: 1471-2377

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