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Table 1 Baseline characteristics of LHI patients with favorable and unfavorable outcome

From: Factors associated with favourable outcome in large hemispheric infarctions

 

Unfavorable (mRS score 4–6) (n = 140)

Favorable (mRS score 0–3) (n = 113)

P value

Age(years)

 Mean ± SD

66.2 ± 14.1

55.8 ± 14.7

< 0.001*

 Median(range)

69(17-99)

57(15–88)

< 0.001†

Female, n(%)

76(54.3)

56(49.6)

0.527‡

Rural population, n(%)

43(30.7)

41(36.3)

0.421‡

Time from onset(hours), median(range)

24(1–720)

26(3–720)

0.014†

NIHSS score on admission, median(range)

17(5–33)

11(4–31)

< 0.001†

SBP on admission (mm Hg)

145.1 ± 26.1

134.7 ± 24.9

0.001*

DBP on admission (mm Hg)

86.9 ± 16.2

80.2 ± 14.9

0.001*

Serum glucose on admission(mmol/L)

8.2 ± 3.3

7.2 ± 3.3

0.015*

Risk factors, n(%)

 Hypertension

83(59.3)

44(38.9)

0.002‡

 Diabetes mellitus

32(22.9)

20(17.7)

0.350‡

 Dyslipidemia

22(15.7)

25(22.1)

0.198‡

 Coronary heart disease

21(15.0)

9(8.0)

0.117‡

 Atrial fibrillation

69(49.3)

42(37.2)

0.057‡

 Rheumatic heart disease

27(19.3)

31(27.4)

0.135‡

 Current smoking

30(21.4)

27(23.9)

0.653‡

 Alcohol consumption

23(16.4)

18(15.9)

0.915 ‡

 Previous all strokes/TIA

27(19.3)

15(13.3)

0.236‡

Stroke in dominant hemisphere, n(%)

65(46.4)

60(53.1)

0.313‡

TOAST classification, n(%)

  

0.222‡

 Large-artery atherosclerosis

27(19.3)

30(26.6)

 

 Cardioembolism

75(53.6)

48(42.5)

 

 Other determined etiology

9(6.4)

5(4.4)

 

 Undetermined etiology

29(20.7)

30(26.6)

 

Statins pretreatment

13(9.3)

13(11.5)

0.678‡

  1. Abbreviations: SBP systolic blood pressure, DBP diastolic blood pressure, NIHSS National Institutes of Health Stroke Scale, GCS Glasgow Coma Scale
  2. *Student t test
  3. †Mann–Whitney U test
  4. ‡χ2 test