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Table 1 Multinomial logistic regression: Influence of the clinical, biochemical and neuroimaging variables on the outcome variables (morbidity and mortality) at 3 months from stroke onset

From: Trends in stroke outcomes in the last ten years in a European tertiary hospital

 

Ischemic stroke

Intracerebral hemorrhage

Morbidity

Mortality

Morbidity

Mortality

OR (95% CI)*

p

OR (95% CI)*

p

OR (95% CI)*

p

OR (95% CI)*

p

WHOLE SAMPLE

 Age (year)

1.03 (1.02–1.04)

< 0.001

1.06 (1.05–1.07)

< 0.001

1.01 (0.99–1.03)

0.148

1.04 (1.02–1.06)

0.001

 Stroke on awakening

1.35 (1.06–1.72)

0.014

1.57 (1.06–2.37)

0.024

    

 Maximum axillary temperature - first 24 h (°C)

1.51 (1.33–1.71)

< 0.001

2.22 (1.06–2.37)

< 0.001

1.32 (0.97–1.79)

0.076

1.92 (1.37–2.68)

< 0.001

 Baseline glycemia (mg/dL)

1.00 (1.00–1.00)

< 0.001

1.00 (1.00–1.00)

< 0.001

    

 Fibrinogen (mg/dL)

    

1.00 (1.00–1.00)

0.019

1.00 (1.00–1.00)

0.065

 White blood cells (×103/mL)

1.11 (1.09–1.14)

< 0.001

1.23 (1.19–1.28)

< 0.001

    

 Baseline volume of hematoma (mL)

    

1.03 (1.02–1.04)

< 0.001

1.05 (1.04–1.06)

< 0.001

PERIOD 2008–2011

 Age (years)

    

1.02 (0.99–1.05)

0.079

1.05 (1.02–1.09)

0.001

 Maximum axillary temperature - first 24 h (°C)

1.20 (0.86–1.64)

0.280

2.37 (1.47–3.82)

< 0.001

    

 Baseline glycemia (mg/dL)

1.00 (1.00–1.00)

0.001

1.00 (1.00–1.01)

0.047

    

 Fibrinogen (mg/dL)

    

1.00 (1.00–1.00)

0.043

1.00 (1.00–1.00)

0.123

 C-reactive protein (mg/L)

1.11 (1.05–1.17)

< 0.001

1.22 (1.14–1.31)

< 0.001

    

TOAST:

  - Lacunar

0.29 (0.13–0.64)

0.002

1.14 (0.13–9.90)

0.905

    

  - Cardioembolic + Indeterminate

1.32 (0.90–1.93)

0.153

3.08 (1.48–6.40)

0.003

    

  - Atherothrombotic + Others

ref.

 

ref.

     

 Ischemic injury volume in 2nd CT (mL)

1.04 (1.03–1.05)

< 0.001

1.05 (1.04–1.06)

< 0.001

    

 Baseline hematoma volume (mL)

    

1.03 (1.01–1.05)

0.001

1.08 (1.05–1.10)

< 0.001

PERIOD 2012–2017

 Age (years)

1.04 (1.03–1.05)

< 0.001

1.07 (1.05–1.09)

< 0.001

1.01 (0.97–1.04)

0.679

1.05 (1.01–1.10)

0.025

 Maximum axillary temperature - first 24 h (°C)

1.12 (1.08–1.15)

< 0.001

1.24 (1.17–1.30)

< 0.001

    

 Baseline glycemia (mg/dL)

1.00 (1.00–1.00)

0.019

1.00 (1.00–1.00)

< 0.001

    

 Fibrinogen (mg/dL)

    

1.00 (1.00–1.01)

0.015

1.00 (0.99–1.00)

0.177

 White blood cells (×103/mL)

1.12 (1.08–1.15)

< 0.001

1.24 (1.17–1.30)

< 0.001

    

 Baseline hematoma volume (mL)

    

1.03 (1.01–1.06)

0.001

1.05 (1.03–1.07)

< 0.001

 Edema volume in 2nd CT (mL)

    

1.02 (0.98–1.05)

0.290

1.04 (1.00–1.07)

0.047

  1. *Adjusted OR. Good outcome was considered the reference category to calculate the ORs (CI 95%)