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Table 3 12-month, seasonal and monthly adherence

From: Seasonal adherence to, and effectiveness of, subcutaneous interferon β-1a administered by RebiSmart® in patients with relapsing multiple sclerosis: results of the 1-year, observational GEPAT-SMART study

  n mean ± sd median min-max
12 month adherence to Rebif® - Rebismart® (Per Protocol Set) 46 98.32 ± 2.628 99.09 90.30–100
Study adherence to Rebif® - Rebismart® (Full Analysis Set) 62 97.93 ± 5.704 100 90.30–100
Seasonal adherence
 Jan-Mar 61 98.02 ± 6.879 100 57.97–100
 Apr-Jun 57 98.36 ± 5.678 100 60.94–100
 Jul-Sep 55 98.58 ± 3.276 100 81.63–100
 Oct-Dec 56 97.91 ± 6.837 100 52.0–100
Monthly adherence
 Jan 60 97.54 ± 10.409 100 33.33–100
 Feb 60 97.56 ± 8.513 100 54.55–100
 March 59 98.34 ± 7.192 100 54.17–100
 April 57 98.60 ± 6.826 100 50.00–100
 May 57 98.67 ± 6.795 100 52.00–100
 June 53 98.21 ± 5.560 100 65.00–100
 July 52 98.45 ± 5.777 100 60.87–100
 August 49 98.873 ± 2.935 100 86.67–100
 September 52 98.46 ± 4.073 100 81.25–100
 October 53 99.01 ± 2.963 100 86.67–100
 November 52 97.933 ± 6.282 100 68.42–100
 December 59 98.14 ± 6.721 100 52.00–100
  1. Annual adherence: 100 × (total no of injections in 12 months) / expected no of infections in the respective months
  2. Seasonal adherence: 100 × (total no of injections in a 3 month-period) / expected no of infections during the same period
  3. Monthly adherence: 100 × (total no of injections in specific month) / expected no of infections