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Table 1 Demographic and clinical characteristics of NMOSD with CTD

From: Neuromyelitis optica spectrum disorders with and without connective tissue disorders

  SS(7) UCTD (7) SLE(3) RA(1)
Gender, n (% female) 7 (100%) 7 (100%) 3 (100%) 1 (100%)
Age at onset, years 41.29 ± 11.73 39.29 ± 9.07 40.67 ± 11.15 45.0 ± 0
Follow-up duration, years 6.07 ± 4.44 5.54 ± 3.79 2.51 ± 1.96 2.0 ± 0
Annualized relapse rate (ARR) 1.87 ± 2.36 0.92 ± 0.51 1.40 ± 0.45 1.5 ± 0
neuropathic pain, n (%) 3 (30%) 6 (60%) 1 (10%) 0 (0%)
Number of attacks 5.29 ± 2.69 3.71 ± 1.70 3.67 ± 3.06 3.0 ± 0
EDSS at nadir 5.29 ± 2.84 4.21 ± 1.82 6.17 ± 2.36 3.0 ± 0
EDSS at last follow-up 4.07 ± 2.99 2.21 ± 0.57 4.17 ± 2.47 2.0 ± 0
Initial presentation, n (%)
 ON 2 (28.57%) 2 (28.57%) 1 (33.33%) 1 (100%)
 Area postrema syndrome 2 (28.57%) 0 (0%) 0 (0%) 0 (0%)
 AM 2 (28.57%) 5 (71.43%) 2 (66.67%) 0 (0%)
 Others 1 (14.29%) 0 (0%) 0 (0%) 0 (0%)
  1. Abbreviations: NMOSD neuromyelitis optica spectrum disorders, CTD connective tissue disorders, SS Sjögren syndrome, UCTD undifferentiated connective tissue disorders, SLE systemic lupus erythematosus, RA rheumatoid arthritis, EDSS Kurtzke Expanded Disability Status Scale, ON optica neuritis, AM acute myelitis