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Table 4 Spinal MRI features between NMOSD with and without CTD

From: Neuromyelitis optica spectrum disorders with and without connective tissue disorders

 

NMOSD (39)

NMOSD with CTD (18)

P

Sagittal location

 length of lesions (VB)

4.44 ± 2.89

7.56 ± 4.79

0.018*

 Short TM at onset, n (%)

7 (17.9%)

1 (5.6%)

0.400

 Initial short TM, n (%)

18 (46.2%)

2 (11.1%)

0.010*

Location of spinal lesions, n (%)

 Cervical cord

13 (33.3%)

2 (11.1%)

0.148

 Cervico-thoracic cord

16 (41.0%)

10 (55.6%)

0.306

 Thoracic cord

10 (25.6%)

6 (33.3%)

0.548

Axial location, n (%)

 Centrally located

38 (97.4%)

18 (100.0%)

1.000

 Peripherally located

1 (2.6%)

0 (0.0%)

1.000

 enhancement

11 (28.2%)

8 (44.4%)

0.227

Acute phase

 T1 dark, n (%)

17 (43.6%)

16 (88.9%)

0.001*

 T2 BSLs, n (%)

14 (35.9%)

13 (72.2%)

0.011*

Chronic phase

 Fragmentation, n (%) or ‘bead-like’ lesions

25 (64.1%)

8 (44.4%)

0.162

 Disappearance, n (%)

9 (23.1%)

7 (38.9%)

0.217

 Atrophy, n (%)

5 (12.8%)

3 (16.7%)

1.000

  1. Abbreviations: NMOSD neuromyelitis optica spectrum disorders, CTD connective tissue disorders, VB vertebral segments, TM transverse myelitis, BSLs bright spotty lesion
  2. *P < 0.05