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Table 4 Spinal MRI features between NMOSD with and without CTD

From: Neuromyelitis optica spectrum disorders with and without connective tissue disorders

  NMOSD (39) NMOSD with CTD (18) P
Sagittal location
 length of lesions (VB) 4.44 ± 2.89 7.56 ± 4.79 0.018*
 Short TM at onset, n (%) 7 (17.9%) 1 (5.6%) 0.400
 Initial short TM, n (%) 18 (46.2%) 2 (11.1%) 0.010*
Location of spinal lesions, n (%)
 Cervical cord 13 (33.3%) 2 (11.1%) 0.148
 Cervico-thoracic cord 16 (41.0%) 10 (55.6%) 0.306
 Thoracic cord 10 (25.6%) 6 (33.3%) 0.548
Axial location, n (%)
 Centrally located 38 (97.4%) 18 (100.0%) 1.000
 Peripherally located 1 (2.6%) 0 (0.0%) 1.000
 enhancement 11 (28.2%) 8 (44.4%) 0.227
Acute phase
 T1 dark, n (%) 17 (43.6%) 16 (88.9%) 0.001*
 T2 BSLs, n (%) 14 (35.9%) 13 (72.2%) 0.011*
Chronic phase
 Fragmentation, n (%) or ‘bead-like’ lesions 25 (64.1%) 8 (44.4%) 0.162
 Disappearance, n (%) 9 (23.1%) 7 (38.9%) 0.217
 Atrophy, n (%) 5 (12.8%) 3 (16.7%) 1.000
  1. Abbreviations: NMOSD neuromyelitis optica spectrum disorders, CTD connective tissue disorders, VB vertebral segments, TM transverse myelitis, BSLs bright spotty lesion
  2. *P < 0.05