Table 2 Results of multivariate logistic regression analysis on 1-year functional outcome after first-ever ischemic stroke. Model A (all observations), Model B (excluding patients that had died early within 0–7 days after hospital admission) and Model C (all observations with subanalysis of the first-ever ischemic stroke “Unknown cause”). Observations with one or more missing variables have been dropped from multivariate analysis. Bold values indicate significance at p < 0.05. Adjusted for age, diabetes mellitus and stroke severity
Predictor variable | Model A | n = 1234 | Model B | n = 1230 | Model C | n = 1234 |
|---|---|---|---|---|---|---|
OR (95% CI) | p value | OR (95% CI) | p value | OR (95% CI) | p value | |
Sex | ||||||
(W vs M) | 1.5 (1.1–2.1) | 0.01 | 1.5 (1.1–2.1) | 0.01 | 1.5 (1.1–2.1) | 0.01 |
Age, years (vs 55–64) | ||||||
< 55 | 0.4 (0.2–0.8) | 0.01 | 0.3 (0.2–0.8) | 0.01 | 0.4 (0.2–0.8) | 0.01 |
65–74 | 1.7 (1.1–2.8) | 0.03 | 1.7 (1.1–2.8) | 0.03 | 1.7 (1.0–2.8) | 0.03 |
75–84 | 3.3 (2.1–5.3) | < 0.01 | 3.3 (2.1–5.3) | < 0.01 | 3.3 (2.0–5.3) | < 0.01 |
≥ 85 | 14.5 (7.4–28.5) | < 0.01 | 14.5 (7.4–28.5) | < 0.01 | 14.4 (7.4–28.3) | < 0.01 |
Regular Physical Activity | ||||||
(No vs Yes) | 1.7 (1.1–2.5) | < 0.01 | 1.7 (1.1–2.5) | < 0.01 | 1.7 (1.1–2.5) | < 0.01 |
Diabetes | ||||||
(Yes vs No) | 1.8 (1.3–2.5) | < 0.01 | 1.9 (1.3–2.95 | < 0.01 | 1.8 (1.3–2.5) | < 0.01 |
Leukocyte count | ||||||
(≥ 9 vs < 9 × 1000/mm3) | 1.4 (1.0–1.9) | 0.04 | 1.4 (1.0–1.9) | 0.05 | 1.4 (1.0–1.9) | 0.04 |
TOAST | ||||||
(vs Small-artery occlusion) | ||||||
Probable atherothrombotic | 1.8 (1.1–2.8) | 0.02 | 1.8 (1.0–2.8) | 0.02 | 1.8 (1.1–2.8) | 0.02 |
Cardioembolic | 1.4 (0.9–2.1) | 0.12 | 1.4 (0.9–2.1) | 0.13 | 1.4 (0.9–2.1) | 0.12 |
Large-arthery Atherosclerosis | 1.4 (0.9–2.3) | 0.17 | 1.4 (0.9–2.3) | 0.17 | 1.4 (0.9–2.3) | 0.17 |
Other determined | 2.0 (0.9–4.4) | 0.09 | 2.0 (0.9–4.4) | 0.09 | 2.0 (0.9–4.4) | 0.09 |
Unkown | 1.5 (0.8–3.0) | 0.21 | 1.5 (0.8–3.0) | 0.21 | ||
Cryptogenic ESUS | 2.2 (0.9–5.5) | 0.10 | ||||
Cryptogenic NON-ESUS | 1.3 (0.5–3.7) | 0.62 | ||||
Undetermined source | 0.9 (0.2–3.8) | 0.94 | ||||
mRS at hospital discharge | ||||||
(≥ 3 vs < 3) | 8.9 (6.0–13.3) | < 0.01 | 8.9 (6.0–13.3) | < 0.01 | 8.9 (6.0–13.4) | < 0.01 |
NIHSS on admission | ||||||
(per point) | 1.2 (1.1–1.2) | < 0.01 | 1.2 (1.1–1.2) | < 0.01 | 1.2 (1.1–1.2) | < 0.01 |