Table 1 Clinical characteristics of all participants (n = 120)
From: Pre-stroke warfarin enhancement of collateralization in acute ischemic stroke: a retrospective study
All (n = 120) | Pre-stroke warfarin users | P value | ||
|---|---|---|---|---|
Yes (n = 29) | No (n = 91) | |||
Demographics, n (%) | ||||
Age > 60 years | 89 (74.2) | 12 (41.4) | 77 (84.6) | < 0.001 |
Male | 37 (30.8) | 8 (27.6) | 29 (31.9) | 0.664 |
Onset to door time < 6 h | 80 (66.7) | 17 (58.6) | 63 (69.2) | 0.291 |
Risk factors, n (%) | ||||
Hypertension | 60 (50.0) | 10 (34.5) | 50 (54.9) | 0.055 |
Diabetes | 16 (13.3) | 3 (10.3) | 13 (14.3) | 0.759 |
Atrial fibrillation | 112 (93.3) | 22 (75.9) | 90 (98.9) | < 0.001 |
Coronary heart disease | 17 (14.2) | 3 (10.3) | 14 (15.4) | 0.76 |
Previous stroke | 16 (13.3) | 2 (6.9) | 14 (15.4) | 0.352 |
Admission examinations, mean ± SD | ||||
INR | 1.15 ± 0.54 | 1.53 ± 1.00 | 1.02 ± 0.09 | < 0.001 |
Systolic blood pressure | 136.88 ± 20.08 | 133.86 ± 23.74 | 137.84 ± 18.81 | 0.356 |
Diastolic blood pressure | 81.31 ± 15.03 | 82.93 ± 13.70 | 80.79 ± 15.47 | 0.507 |
Serum glucose | 7.85 ± 2.40 | 7.45 ± 2.71 | 7.97 ± 2.29 | 0.311 |
Triglyceride | 1.53 ± 1.60 | 1.90 ± 2.65 | 1.40 ± 1.08 | 0.72 |
Cholesterol | 3.97 ± 0.99 | 3.91 ± 1.29 | 3.98 ± 0.88 | 0.325 |
HDL-C | 1.38 ± 0.56 | 1.36 ± 0.79 | 1.39 ± 0.47 | 0.26 |
LDL-C | 2.25 ± 0.72 | 2.16 ± 0.65 | 2.29 ± 0.74 | 0.402 |
Clinical factors, n (%) | ||||
Thrombus location on CTA | 0.078 | |||
ICA + M1 | 28 (23.3) | 6 (20.7) | 22 (24.2) | |
M1 | 54 (45.0) | 9 (31.0) | 45 (49.5) | |
M2 | 38 (31.7) | 14 (48.3) | 24 (26.3) | |
NIHSS scores | 13 (7–18) | 12 (8–16) | 13 (7–18) | |
Thrombolysis | 22 (18.3) | 4 (13.8) | 18 (19.8) | 0.468 |
Intracranial hemorrhage | 27 (22.5) | 5 (17.2) | 22 (24.2) | 0.436 |
Pre-stroke medications, n (%) | ||||
Antihypertensive drugs | 49 (40.8) | 10 (34.5) | 39 (42.9) | 0.424 |
Antidiabetics | 14 (11.7) | 3 (10.3) | 11 (12.1) | 0.549 |
Antiplatelet drugs | 21 (17.5) | 2 (6.90) | 19 (20.9) | 0.084 |
Statins | 21 (17.5) | 7 (24.1) | 14 (15.4) | 0.28 |