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Table 2 Associated factors with collateral circulation in acute ischemic stroke patients

From: Pre-stroke warfarin enhancement of collateralization in acute ischemic stroke: a retrospective study

 

Poor (n = 43)

Moderate (n = 52)

Good (n = 25)

P value

Univariate logistic analysis

Poor vs. not poor rLMC

Good vs. not good rLMC

Age > 60 years

30 (69.8)

40 (76.9)

15 (60.0)

0.269

0.85 (0.36–1.97)

0.54 (0.21–1.38)

Hypertension history

24 (55.8)

25 (48.1)

11 (44.0)

0.601

1.36 (0.61–3.07)

0.85 (0.33–2.21)

Diabetes

6 (13.9)

8 (15.4)

2 (8.0)

0.664

0.89 (0.28–2.80)

0.48 (0.09–2.44)

Atrial fibrillation

42 (97.7)

48 (92.3)

22 (88.0)

0.282

3.50 (0.38–32.55)

0.61 (0.13–2.97)

Coronary heart disease

9 (20.9)

8 (15.4)

0 (0.0)

0.023

1.46 (0.51–4.17)

Previous stroke

5 (11.6)

10 (19.2)

1 (4.00)

0.168

0.55 (0.17–1.76)

0.18 (0.02–1.45)

Systolic blood pressure

34.98 ± 19.98

137.77 ± 21.91

38.28 ± 16.43

0.74

0.99 (0.95–1.02)

1.02 (0.97–1.07)

Diastolic blood pressure

82.67 ± 16.53

80.54 ± 14.04

80.56 ± 14.78

0.761

1.00 (0.96–1.05)

0.93 (0.87–0.99)

Serum glucose

8.33 ± 2.63

7.44 ± 2.17

7.84 ± 2.41

0.252

1.12 (0.98–1.40)

1.09 (0.88–1.34)

Triglyceride

1.51 ± 1.40

1.48 ± 1.99

1.63 ± 0.95

0.106

1.01 (0.69–1.47)

1.06 (0.79–1.39)

Cholesterol

3.92 ± 0.84

3.79 ± 1.09

4.43 ± 0.86

0.173

1.18 (0.75–1.85)

1.83 (1.16–3.40)

HDL-C

1.36 ± 0.44

1.38 ± 0.64

1.44 ± 0.57

0.864

0.91 (0.43–1.94)

1.17 (0.52–2.63)

LDL-C

2.35 ± 0.74

2.04 ± 0.68

2.54 ± 0.67

0.008

1.33 (0.79–2.24)

1.99 (1.07–3.72)

Antihypertensive drugs

17 (39.5)

22 (42.3)

10 (40.0)

0.959

0.89 (0.39–2.03)

0.91 (0.34–2.40)

Antidiabetics

6 (13.9)

7 (13.5)

1 (4.00)

0.44

1.04 (0.32–3.37)

0.27 (0.03–2.31)

Antiplatelet drugs

5 (11.6)

11 (21.2)

5 (20.0)

0.449

0.49 (0.16–1.54)

0.93 (0.29–3.05)

Statins

3 (6.9)

13 (25.0)

5 (20.0)

0.068

0.33 (0.06–0.85)

1.23 (0.40–3.77)

Warfarin

5 (11.6)

15 (28.9)

9 (36.0)

0.045

0.21 (0.10–0.83)

2.11 (0.81–5.48)

  1. HDL high density lipoprotein, LDL high density lipoprotein, CTA computer tomography angiography, ICA internal carotid artery, NIHSS National Institutes of Health Stroke Scale, LMC leptomeningeal collateral