BMC Neurology

Table 1 Patient demographics and plaque characteristics

From: Plasma homocysteine levels and intracranial plaque characteristics: association and clinical relevance in ischemic stroke

Variables	Symptomatic group (n = 75)	Asymptomatic group (n = 19)	P value
Male, n (%)	54 (72.0%)	14 (73.7%)	0.883
Age, (Mean ± SD), y	59.7 ± 12.8	62.3 ± 16.6	0.454
Hypertension, n (%)	53 (70.7%)	16 (84.2%)	0.233
Diabetes mellitus, n (%)	28 (37.3%)	9 (47.4%)	0.424
Hyperlipidemia, n (%)	35 (46.7%)	10 (52.6%)	0.642
Current smoker, n (%)	24 (32.0%)	4 (21.1%)	0.351
Serum creatinine (μmol/L)	69.84 ± 16.31	71.32 ± 11.97	0.712
Homocysteine, (μmol/L)^a	16.78 ± 5.52	13.63 ± 5.01	0.026
High Hcy, n (%)	48 (64.0%)	4 (21.1%)	0.001
Normal Hcy, n (%)	27 (36.0%)	15 (78.9%)	0.001
Plaque characteristics^b
Strong enhancement	54 (72.0%)	4 (21.1%)	< 0.001
Presence of T1 hyperintense	29 (38.7%)	2 (10.5%)	0.020
Presence of T2 hyperintense	38 (50.7%)	8 (42.1%)	0.505
Stenosis ratio (%)	61.7 ± 31.3	52.3 ± 30.0	0.303

Note: ^a The normal range of plasma Hcy is 5–15 μmol/L. High Hcy is defined as Hcy levels above 15 μmol/L. ^b Strong plaque enhancement, enhancement was greater than or equal to that of pituitary stalk; lesion T2 hyperintense components: presence or absence of T2 hyperintense band adjacent to the lumen; lesion T1 hyperintense components: presence or absence of T1 hyperintense on unenhanced T1 images with fat-suppression

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