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Table 2 Clinical characteristics, medical history, and presenting symptoms of acute ischemic stroke patients with a history of hypertension stratified by rtPA status and telestroke status

From: Predictors of thrombolysis in the telestroke and non telestroke settings for hypertensive acute ischemic stroke patients

Characteristic

Non-Telestroke

Telestroke

No rtPA (N = 266)

rtPA (N = 168)

P-Value

No rtPA (N = 29)

rtPA (N = 238)

P-Value

Patient Age in Years

 Mean ± SD

71.4 ± 13.9

68 ± 14.3

0.015*

65.9 ± 13.6

66.1 ± 13.5

0.932

Age Group: No. (%)

 < 50 years

27 (10.2)

18 (10.7)

0.007*

2 (6.9)

29 (12.2)

0.268

 50–59

25 (9.4)

31 (18.5)

 

9 (31)

38 (16)

 

 60–69

47 (17.7)

41 (24.4)

 

7 (24.1)

69 (29)

 

 70–79

83 (31.2)

35 (20.8)

 

5 (17.2)

62 (26.1)

 

 ≥ 80

84 (31.6)

43 (25.6)

 

6 (20.7)

40 (16.8)

 

Gender: No. (%)

 Male

121 (45.5)

82 (48.8)

0.499

15 (51.7)

124 (52.1)

0.969

 Female

145 (54.5)

86 (51.2)

 

14 (48.3)

114 (47.9)

 

Race: No. (%)

 Caucasian

207 (77.8)

139 (82.7)

0.451

22 (75.9)

187 (78.6)

0.725

 African-American

33 (12.4)

17 (10.1)

 

4 (13.8)

42 (17.6)

 

 Other

3 (1.1)

0 (0)

 

1 (3.4)

4 (1.7)

 

Hispanic Ethnicity: No. (%)

3 (1.1)

2 (1.2)

0.952

0 (0)

6 (2.5)

0.387

Body Mass Index

 Mean ± SD

28 ± 6.7

28.6 ± 6.7

0.312

31.5 ± 7.2

30.7 ± 7.3

0.596

Medical History: No. (%)

 Atrial Fib/Flutter

81 (30.5)

37 (22)

0.055

4 (13.8)

27 (11.3)

0.698

 Carotid Artery Stenosis

21 (7.9)

4 (2.4)

0.016*

1 (3.4)

15 (6.3)

0.541

 Congestive Heart Failure

45 (16.9)

16 (9.5)

0.031*

6 (20.7)

27 (11.3)

0.149

 Coronary Artery Disease

103 (38.7)

70 (41.7)

0.542

11 (37.9)

95 (39.9)

0.837

 Depression

1 (0.4)

0 (0)

0.426

4 (13.8)

44 (18.5)

0.534

 Diabetes

103 (38.7)

62 (36.9)

0.704

16 (55.2)

107 (45)

0.297

 Dyslipidemia

160 (60.2)

99 (58.9)

0.8

16 (55.2)

152 (63.9)

0.36

 Family History of Stroke

22 (8.3)

13 (7.7)

0.843

0 (0)

32 (13.4)

0.035*

 Hormone Replacement Therapy

3 (1.1)

0 (0)

0.167

0 (0)

8 (3.4)

0.316

 Migraine

2 (0.8)

5 (3)

0.073

1 (3.4)

7 (2.9)

0.88

 Obesity

93 (35)

58 (34.5)

0.926

15 (51.7)

137 (57.6)

0.549

 Peripheral Vascular Disease

22 (8.3)

14 (8.3)

0.982

1 (3.4)

24 (10.1)

0.247

 Previous Stroke

100 (37.6)

39 (23.2)

0.002*

7 (24.1)

59 (24.8)

0.939

 Previous TIA

32 (12)

27 (16.1)

0.231

4 (13.8)

28 (11.8)

0.751

 Prosthetic Heart Valve

9 (3.4)

0 (0)

0.016*

0 (0)

1 (0.4)

0.727

 Renal Insufficiency

28 (10.5)

5 (3)

0.004*

1 (3.4)

16 (6.7)

0.495

 Sleep Apnea

0 (0)

0 (0)

N/A

1 (3.4)

11 (4.6)

0.773

 Smoking

62 (23.3)

53 (31.5)

0.058

9 (31)

58 (24.4)

0.434

 Substance Abuse

11 (4.1)

6 (3.6)

0.768

1 (3.4)

6 (2.5)

0.768

Initial NIH Stroke Scale

 Mean ± SD

10.1 ± 9

11.5 ± 7.9

0.124

9.2 ± 8.3

9.5 ± 8.3

0.851

Initial Labs & Vitals

 Total Cholesterol

165 ± 52.8

164.7 ± 43.2

0.956

180.7 ± 50.2

164.9 ± 41.2

0.068

 Triglycerides

132 ± 89.5

134.9 ± 89.8

0.759

147.4 ± 72.9

147.7 ± 106.1

0.987

 HDL

40.7 ± 14.6

41.1 ± 13

0.834

42 ± 14.1

40 ± 12.5

0.44

 LDL

97.9 ± 36.7

98.3 ± 37.8

0.91

111.6 ± 45.3

99 ± 33.8

0.08

 Lipids

6.5 ± 1.8

6.3 ± 1.5

0.215

6.7 ± 1.9

6.4 ± 1.7

0.539

 Blood Glucose

158.9 ± 95.1

138.6 ± 68.7

0.011*

164.4 ± 113.6

135.9 ± 65.4

0.203

 Creatinine

1.5 ± 1.4

1.2 ± 0.5

0.001*

1.4 ± 1.8

1.1 ± 0.5

0.356

 INR

1.2 ± 0.6

1.1 ± 0.1

0.001*

1.1 ± 0.4

1 ± 0.1

0.588

 Heart Rate

83.4 ± 19

81.5 ± 17.7

0.284

76 ± 13.9

78.4 ± 16.2

0.444

 Systolic Blood Pressure

154.5 ± 30.7

158.3 ± 31.2

0.217

152 ± 24.9

147.8 ± 23.8

0.38

 Diastolic Blood Pressure

82.6 ± 21

85.2 ± 19.8

0.214

78.8 ± 13.8

79.9 ± 16.6

0.721

Medications Prior to Admission: No. (%)

 Antiplatelet or Anticoagulant

162 (60.9)

94 (56)

0.307

18 (62.1)

133 (55.9)

0.526

 Antihypertensive

222 (83.5)

147 (87.5)

0.25

25 (86.2)

208 (87.4)

0.856

 Cholesterol Reducer

137 (51.5)

85 (50.6)

0.854

18 (62.1)

130 (54.6)

0.446

 Diabetic Medication

74 (27.8)

45 (26.8)

0.814

11 (37.9)

88 (37)

0.92

Ambulation Status Prior to Event: No. (%)

 Ambulate Independently

218 (82)

159 (94.6)

0.002*

25 (86.2)

227 (95.4)

0.246

 Ambulate With Assistance

18 (6.8)

4 (2.4)

 

1 (3.4)

3 (1.3)

 

 Unable to Ambulate

16 (6)

3 (1.8)

 

2 (6.9)

5 (2.1)

 

 Not Documented

14 (5.3)

2 (1.2)

 

1 (3.4)

3 (1.3)

 

Ambulation Status on Admission: No. (%)

 Ambulate Independently

46 (17.3)

14 (8.3)

< 0.001*

11 (37.9)

44 (18.5)

0.023*

 Ambulate With Assistance

48 (18)

15 (8.9)

 

4 (13.8)

49 (20.6)

 

 Unable to Ambulate

95 (35.7)

67 (39.9)

 

10 (34.5)

62 (26.1)

 

 Not Documented

77 (28.9)

72 (42.9)

 

4 (13.8)

83 (34.9)

 

Ambulation Status on Discharge: No. (%)

 Ambulate Independently

94 (35.3)

68 (40.5)

0.45

15 (51.7)

117 (49.2)

0.736

 Ambulate With Assistance

78 (29.3)

50 (29.8)

 

7 (24.1)

77 (32.4)

 

 Unable to Ambulate

64 (24.1)

38 (22.6)

 

4 (13.8)

29 (12.2)

 

 Not Documented

30 (11.3)

12 (7.1)

 

3 (10.3)

15 (6.3)

 

First Care Received: No. (%)

 Emergency Department

242 (91)

153 (91.1)

0.973

18 (62.1)

60 (25.2)

< 0.001*

 Direct Admission

24 (9)

15 (8.9)

 

11 (37.9)

178 (74.8)

 

Improved Ambulation

142 (53.4)

110 (65.5)

0.013*

20 (69)

168 (70.6)

0.857

  1. Continuous variables are represented as Mean ± S.D. and comparisons between groups are made with a Student’s T Test. Discrete variables are represented as Count (Percent Frequency) and comparisons between groups were made using Pearson’s Chi-Squared
  2. *P<0.05