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Table 3 Individual characteristics at enrollment and their association with death (n = 95)

From: Mortality & recurrent seizure risk after new-onset seizure in HIV-positive Zambian adults

Characteristic

Hazard Ratio [95% CI]

P-value a

Gender, female

0.9 [0.5–1.7]

0.745

Age, mean

1.01 [0.98–1.05]

0.383

WHO HIV clinical stage III or IVb

19.1 [1.1–333.4]

0.01

cART use at enrollment

1.5 [0.8–2.9]

0.240

Karnofsky score < 50 at enrollment

1.8 [0.9–3.8]

0.125

Seizure severity at enrollment

 Brief, Single

Referent

0.173

 Multiple, prolonged

1.7 [0.7–3.9]

 

 Status epilepticus

2.6 [0.96–7.3]

 

CNS opportunistic infection

0.9 [0.4–2.2]

0.889

Unknown etiology

2.2 [1.1–4.4]

0.025

Among those with CSF (n = 61)

2.1 [0.8–5.3]

0.129

  1. Data is presented as the hazards ratio for the listed characteristic versus the null with a hazards ratio of 1.0 indicating no difference. CI confidence interval, WHO World Health Organization, cART combination antiretroviral therapy, CNS central nervous system, CSF cerebrospinal fluid
  2. aLog-Rank Tests bAs compared to WHO clinical stage I or II