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Table 3 Allelic distribution of the t-PA and PAI-1 gene between TLE patients and controls

From: Role of t-PA and PAI-1 variants in temporal lobe epilepsy in Chinese Han population

Gene

SNP

Allele

Cases

(242 alleles across 121 subjects)

n (% of population)

Controls

(292 alleles across

146 subjects)

n (% of population)

OR(95%CI)

χ2

p-value

t-PA

rs2020918

C

171(70.7)

237(81.2)

   

T

71(29.3)

55(18.9)

1.789(1.195–2.678)

8.098

0.004

rs4646972

311 bp

112(46.3)

185(63.4)

   

–

130(53.7)

107(36.6)

2.007(1.418–2.840)

15.630

0.000

PAI-1

rs1799768

–

139(57.4)

169(57.9)

   

G

103(42.6)

123(42.1)

1.018(0.721–1.437)

0.01

0.919