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Table 2 Association between individual items of SCOPA-AUT and olfactory dysfunction

From: Association between autonomic dysfunction and olfactory dysfunction in Parkinson’s disease in southern Chinese

Questions Correlations with SS-16a Correlations with individualb Correlations with individual (adjusted)b,c
p value OR 95% CI p value OR 95% CI
Question 1 “difficulty swallowing or have you choked” 0.306 0.950 1.05 (0.22, 5.58) 0.954 1.05 (0.21, 5.96)
Question 2 “saliva dribbled out of your mouth” 0.013 0.285 1.55 (0.70, 3.46) 0.439 1.16 (0.60, 3.18)
Question 3 “food become stuck in your throat” 0.078 0.273 2.52 (0.55, 17.82) 0.153 4.92 (0.93, 70.09)
Question 4 “full very quickly during a meal” 0.144 0.230 1.91 (0.68, 5.91) 0.264 1.87 (0.64, 6.04)
Question 5 “constipation” 0.178 0.119 1.89 (0.85, 4.25) 0.284 1.62 (6.69, 3.97)
Question 6 “strain hard to pass stools” 0.006 0.030 2.45 (1.10, 5.60) 0.066 2.24 (0.96, 5.35)
Question 7 “involuntary loss of stools” 0.194 0.996 0.996
Question 8 “difficulty retaining urine” 0.025 0.405 1.43 (0.62, 3.38) 0.521 1.33 (0.56, 3.18)
Question 9 “involuntary loss of urine” 0.705 0.182 0.49 (0.16, 1.39) 0.091 0.37 (0.11, 1.14)
Question 10 “feeling that after passing urine your bladder was not completely empty” 0.005 0.006 4.10 (1.56, 12.21) 0.011 3.91 (1.45, 12.00)
Question 11 “the stream of urine is weak” 0.022 0.318 1.73 (0.61, 5.37) 0.286 1.83 (0.62, 5.95)
Question 12 “pass urine again within 2 h of the previous time” 0.064 0.915 0.95 (0.40, 2.30) 0.682 0.82 (0.31, 2.14)
Question 13 “have to pass urine at night” < 0.001 0.115 1.93 (0.86, 4.40) 0.144 1.85 (0.81, 4.27)
Question 14 “lightheaded when standing up” 0.038 0.030 2.94 (1.15, 8.26) 0.027 3.27 (1.20, 10.05)
Question 15 “lightheaded after standing for some time” 0.168 0.994 0.996
Question 16 “fainted in the past 6 months” 0.733 0.863 0.78 (0.03, 20.15) 0.815 1.49 (0.05, 111.72)
Question 17 “perspire excessively during the day” 0.404 0.115 0.52 (0.23, 1.17) 0.126 0.52 (0.23, 1.19)
Question 18 “perspire excessively during the night” 0.789 0.957 0.98 (0.40, 2.40) 0.963 1.02 (0.42, 2.55)
Question 19 “oversensitive to bright light” 0.490 0.867 0.90 (0.28, 3.02) 0.994 1.00 (0.29, 3.57)
Question 20 “have trouble tolerating cold” 0.799 0.690 1.20 (0.49, 3.00) 0.626 1.25 (0.51, 3.17)
Question 21 “have trouble tolerating heat” 0.852 0.498 0.73 (0.29, 1.84) 0.517 0.73 (0.28, 1.89)
Question 22 “impotent (for men)” 0.984 0.251 0.45 (0.10, 1.72) 0.221 0.41 (0.09, 1.65)
Question 23 “unable to ejaculate (for men)” 0.942 0.251 0.45 (0.10, 1.72) 0.221 0.41 (0.09, 1.65)
Question 23a “taken medication for an erection disorder (for men)” 1.000 1.000 1.000
Question 24 “vagina too dry during sexual activity (for women)” 0.463 0.163 2.81 (0.71, 14.15) 0.177 2.77 (0.68, 14.35)
Question 25 “difficulty reaching an orgasm (for women)” 0.463 0.163 2.81 (0.71, 14.15) 0.177 2.77 (0.68, 14.35)
Question 26a “use medication for constipation” 0.310 0.313 1.65 (0.64, 4.51) 0.501 1.42 (0.52, 4.06)
Question 26b “use medication for urinary problems” 0.381 0.293 3.31 (0.47, 66.00) 0.261 3.62 (0.50, 72.98)
Question 26c “use medication for blood pressure” 0.867 0.867 0.90 (0.28, 3.02) 0.877 0.91 (0.28, 3.08)
Question 26d “use medication for other symptoms” 1.000 1.000 1.000
  1. CI confidence interval, OR odds ratio, SCOPA-AUT Scales for Outcomes in Parkinson’s Disease-Autonomic questionnaire, SS-16 Sniffin’ Sticks 16 items
  2. a p value of the linear correlation between the score of each question and SS-16 scores
  3. b the association between each symptom described by each question and olfactory dysfunction using binomial logistic regression
  4. c adjust disease duration, gender and age