rs1234313 and rs45454293 are risk factors of cerebral arterial thrombosis, large artery atherosclerosis, and carotid plaque in the Han Chinese population: a case-control study

Table 5 Association of TNFSF4 rs4545293 polymorphism with types of carotid plaque in patients with ischemic stroke

Genetic model	Comparison	RRR^a vs. controls	p-value	95% CI lower	95%CI Upper
Single plaque
allelic	G vs A	1.047	0.158	0.982	1.115
Dominant	GG/GA vs AA	1.003	0.852	0.975	1.031
genotypic	GA vs AA	0.999	0.992	0.862	1.158
	GG vs AA	1.004	0.800	0.971	1.039
Multi plaque
allelic	G vs A	0.994	0.827	0.940	1.051
Dominant	GG/GA vs AA	0.993	0.621	0.968	1.020
genotypic	GA vs AA	0.973	0.626	0.872	1.086
	GG vs AA	0.991	0.622	0.958	1.026
Thick plaque
allelic	G vs A	1.076	0.010*	1.018	1.137
Dominant	GG/GA vs AA	1.002	0.890	0.973	1.032
genotypic	GA vs AA	0.977	0.825	0.792	1.204
	GG vs AA	1.004	0.800	0.971	1.039
Calcification
allelic	G vs A	0.990	0.760	0.926	1.058
Dominant	GG/GA vs AA	0.998	0.893	0.971	1.026
genotypic	GA vs AA	0.996	0.936	0.894	1.108
	GG vs AA	0.997	0.881	0.962	1.034

TNFSF4 Tumor necrosis factor super family member 4, RRR relative risk ration, CI Confidence interval; *, p < 0.05, indicating a significant difference

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