Table 2 Common medical comorbidities at baseline and selected follow-up in patients with and without BD
Baseline (6-months pre-index date) | Selected Follow-up (12 months post-index) | |||||
|---|---|---|---|---|---|---|
With BD (N = 16,440) | Without BD (N = 86,962) | P Value | With BD (N = 11,440) | Without BD (N = 54,516) | P Value | |
Medical Comorbidities (%) | ||||||
Hypertension | 55.3% | 58.0% | < 0.001 | 80.6% | 77.7% | < 0.001 |
Dyslipidemia | 23.4% | 26.7% | < 0.001 | 41.2% | 42.8% | 0.001 |
Diabetes | 24.1% | 25.5% | < 0.001 | 30.8% | 30.3% | 0.332 |
Cerebrovascular disease | 20.2% | 21.0% | 0.019 | 39.7% | 34.5% | < 0.001 |
Urinary tract infection | 17.8% | 15.4% | < 0.001 | 39.6% | 27.2% | < 0.001 |
Chronic Pulmonary Disease | 14.4% | 16.3% | < 0.001 | 25.1% | 24.1% | 0.021 |
Congestive Heart Failure | 12.9% | 13.7% | 0.004 | 23.7% | 20.9% | < 0.001 |
Peripheral vascular disease | 8.4% | 8.9% | 0.068 | 18.4% | 15.6% | < 0.001 |
Hip fracture and other fractures | 10.1% | 9.5% | 0.024 | 21.1% | 16.0% | < 0.001 |
Malignancy | 8.0% | 9.8% | < 0.001 | 11.6% | 13.3% | < 0.001 |
Malnutrition | 2.4% | 2.0% | 0.0004 | 6.1% | 3.8% | < 0.001 |
Pneumonia | 6.8% | 7.1% | 0.231 | 17.4% | 13.3% | < 0.001 |
Psychiatric Conditions (%) | ||||||
Mood disorder | 16.7% | 13.3% | < 0.001 | 41.6% | 25.7% | < 0.001 |
Depression | 16.0% | 12.4% | < 0.001 | 40.4% | 24.4% | < 0.001 |
Delirium | 6.95% | 4.57% | < 0.001 | 21.0% | 9.5% | < 0.001 |
Psychotic disorders | 19.0% | 12.0% | < 0.001 | 46.7% | 21.4% | < 0.001 |
Psychosis | 16.1% | 10.1% | < 0.001 | 39.7% | 17.8% | < 0.001 |
Altered Mental State | 16.9% | 11.4% | < 0.001 | 43.1% | 21.6% | < 0.001 |
Anxiety Disorder | 9.1% | 7.2% | < 0.001 | 26.1% | 14.6% | < 0.001 |