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Table 2 Laboratory blood test of the ESRD patients with and without RLS

From: Restless legs syndrome in end stage renal disease patients undergoing hemodialysis

  Patients with ESRD, N (%)  
Variables RLS – (n = 109) RLS + (n = 28) p value
Blood Urea Nitrogen mmol/L 27.48 (23.31-31.35) 29.33 (27.3-34.2) 0.014
Pre-dialysis Creatinine mg/dl 1037 (874.5-1204.5) 1053 (900-1193.5) 0.852
Pro-dialysis Creatinine mg/dl 350 (276-418) 327 (247-462) 0.378
D-value of Creatinine mg/dl 685 (559.5-791.5) 699 (641.25-805.75) 0.370
Calcium mg/dL 2.31 ± 0.26 2.32 ± 0.26 0.744
Phosphorus mg/dL 1.90 ± 0.47 2.11 ± 0.70 0.155
Ca*P product mg2/dL2 4.41 ± 1.30 4.92 ± 1.75 0.157
Albumin g/dL 39.24 ± 4.24 39.70 ± 6.29 0.650
Alkaline Phosphatase U/L 73 (54-93.5) 75 (61-98.75) 0.523
Hemoglobin g/L 100.13 ± 15.54 105.43 ± 22.1 0.240
Serum Iron μmol/L 13.2 (9.45-16.3) 15.41 (12.5-18.0) 0.034
Ferritin μg/L 194 (68.85-335.3) 122.5 (53.8-232.99) 0.371
Transferrin g/L 2.11 (1.83-2.36) 2.14 (1.78-2.45) 0.953
TIBC μmol/L 47.02 ± 8.49 48.51 ± 9.67 0.424
Parathyroid Hormone pg/mL 203.9 (65.91-472.1) 258.3 (62.95-574.1) 0.522
Kt/V   1.53 ± 0.61 1.49 ± 0.34 0.783
URR % 70.19 ± 8.15 70.27 ± 8.05 0.967
  1. Abbreviations: ESRD end stage renal disease, RLS restless legs syndrome, RLS- without RLS, RLS+ with RLS, Ca*P product calcium phosphorus product, TIBC total iron-binding capacity, Kt/V is a number used to quantify hemodialysis (K, dialyzer clearance of urea; t, dialysis time; V, volume of distribution of urea, approximately equal to patient’s total body water); URR, urea reduction ratio